[HTML][HTML] Biomimetics of the pulmonary environment in vitro: A microfluidics perspective
The entire luminal surface of the lungs is populated with a complex yet confluent,
uninterrupted airway epithelium in conjunction with an extracellular liquid lining layer that …
uninterrupted airway epithelium in conjunction with an extracellular liquid lining layer that …
Electric cell-substrate impedance sensing (ECIS) as a platform for evaluating barrier-function susceptibility and damage from pulmonary atelectrauma
E Yamaguchi, J Yao, A Aymond, DB Chrisey… - Biosensors, 2022 - mdpi.com
Biophysical insults that either reduce barrier function (COVID-19, smoke inhalation,
aspiration, and inflammation) or increase mechanical stress (surfactant dysfunction) make …
aspiration, and inflammation) or increase mechanical stress (surfactant dysfunction) make …
Propagation of air fingers into an elastorigid Y-bifurcation
We study experimentally the propagation of an air finger through the Y-bifurcation of an
elastic, liquid-filled Hele-Shaw channel as a benchtop model of airway reopening. With …
elastic, liquid-filled Hele-Shaw channel as a benchtop model of airway reopening. With …
Surfactant aerosol therapy for nRDS and ARDS
DB Yeates - Inhalation aerosols, 2019 - taylorfrancis.com
In premature babies with respiratory distress syndrome (RDS) and in patients with an
inflammatory response to an acute lung injury, the absence or degradation of surfactant in …
inflammatory response to an acute lung injury, the absence or degradation of surfactant in …
The propagation of air fingers into an elastic branching network
We study experimentally the propagation of an air finger through the Y-bifurcation of an
elastic, liquid-filled Hele-Shaw channel, as a benchtop model of airway reopening. With …
elastic, liquid-filled Hele-Shaw channel, as a benchtop model of airway reopening. With …
Engineered airway models to study liquid plug splitting at bifurcations: Effects of orientation and airway size
Delivery of biological fluids, such as surfactant solutions, into lungs is a major strategy to
treat respiratory disorders including respiratory distress syndrome that is caused by …
treat respiratory disorders including respiratory distress syndrome that is caused by …
Microscale distribution and dynamic surface tension of pulmonary surfactant normalize the recruitment of asymmetric bifurcating airways
E Yamaguchi, LP Nolan… - Journal of Applied …, 2017 - journals.physiology.org
We investigate the influence of bifurcation geometry, asymmetry of daughter airways,
surfactant distribution, and physicochemical properties on the uniformity of airway …
surfactant distribution, and physicochemical properties on the uniformity of airway …
The influence of tethering and gravity on the stability of compliant liquid-lined airways
J Whang, C Faulman, TA Itin, DP Gaver III - Journal of Biomechanics, 2017 - Elsevier
This study revolves around two simple questions: 1) how does pulmonary airway
recruitment/de-recruitment (RecDer) depend on the tethering support provided by …
recruitment/de-recruitment (RecDer) depend on the tethering support provided by …
[PDF][PDF] Personal Statement
C Parker - Cancer Research, 2005 - obrien.urology.wisc.edu
Research in my laboratory is focused on understanding the biology of the prostate gland at
the molecular level. Interest in understanding the biology of the prostate is driven both by the …
the molecular level. Interest in understanding the biology of the prostate is driven both by the …
Engineered Airway Models to Study Liquid Plug Splitting at Bifurcations: Effects of Orientation and Airway Size
Delivery of biological fluids, such as surfactant solutions, into lungs is a major strategy to
treat respiratory disorders including respiratory distress syndrome that is caused by …
treat respiratory disorders including respiratory distress syndrome that is caused by …