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[HTML][HTML] Kidney and eye diseases: common risk factors, etiological mechanisms, and pathways
Chronic kidney disease is an emerging health problem worldwide. The eye shares striking
structural, developmental, and genetic pathways with the kidney, suggesting that kidney …
structural, developmental, and genetic pathways with the kidney, suggesting that kidney …
Medical management of glaucoma in the 21st century from a Canadian perspective
P Harasymowycz, C Birt, P Gooi… - Journal of …, 2016 - Wiley Online Library
Glaucoma is a medical term describing a group of progressive optic neuropathies
characterized by degeneration of retinal ganglion cells and retinal nerve fibre layer and …
characterized by degeneration of retinal ganglion cells and retinal nerve fibre layer and …
Epidemiology of glaucoma in sub-saharan Africa: prevalence, incidence and risk factors
Purpose: The purpose of this study is to review the epidemiology of different types of
glaucoma relevant to Sub-Saharan Africa (SSA) and to discuss the evidence regarding the …
glaucoma relevant to Sub-Saharan Africa (SSA) and to discuss the evidence regarding the …
Sustained release ocular drug delivery systems for glaucoma therapy
ZK Al-Qaysi, IG Beadham, SL Schwikkard… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Glaucoma is a group of progressive optic neuropathies resulting in irreversible
blindness. It is associated with an elevation of intraocular pressure (> 21 mm Hg) and optic …
blindness. It is associated with an elevation of intraocular pressure (> 21 mm Hg) and optic …
All roads lead to glaucoma: Induced retinal injury cascades contribute to a common neurodegenerative outcome
Glaucoma describes a distinct optic neuropathy with complex etiology and a variety of
associated risk factors, but with similar pathological endpoints. Risk factors such as age …
associated risk factors, but with similar pathological endpoints. Risk factors such as age …
[HTML][HTML] Topical Coenzyme Q10 demonstrates mitochondrial-mediated neuroprotection in a rodent model of ocular hypertension
BM Davis, K Tian, M Pahlitzsch, J Brenton… - Mitochondrion, 2017 - Elsevier
Abstract Coenzyme Q10 (CoQ10) is a mitochondrial-targeted antioxidant with known
neuroprotective activity. Its ocular effects when co-solubilised with α–tocopherol …
neuroprotective activity. Its ocular effects when co-solubilised with α–tocopherol …
Tetrahedral framework nucleic acids prevent retina ischemia-reperfusion injury from oxidative stress via activating the Akt/Nrf2 pathway
X Qin, N Li, M Zhang, S Lin, J Zhu, D **ao, W Cui… - Nanoscale, 2019 - pubs.rsc.org
Retinal ischemia-reperfusion (I/R) injuries are involved in the universal pathological
processes of many ophthalmic diseases, including glaucoma, diabetic retinopathy, and …
processes of many ophthalmic diseases, including glaucoma, diabetic retinopathy, and …
[HTML][HTML] Sphingolipids as critical players in retinal physiology and pathology
Sphingolipids have emerged as bioactive lipids involved in the regulation of many
physiological and pathological processes. In the retina, they have been established to …
physiological and pathological processes. In the retina, they have been established to …
Intracameral sustained-release bimatoprost implant delivers bimatoprost to target tissues with reduced drug exposure to off-target tissues
JR Seal, MR Robinson, J Burke… - Journal of Ocular …, 2019 - liebertpub.com
Purpose: To explore the ocular distribution of bimatoprost after intracameral administration
of a biodegradable sustained-release bimatoprost implant (Bimatoprost SR) versus …
of a biodegradable sustained-release bimatoprost implant (Bimatoprost SR) versus …
The role of neuroinflammation in glaucoma: an update on molecular mechanisms and new therapeutic options
T Rolle, A Ponzetto, L Malinverni - Frontiers in Neurology, 2021 - frontiersin.org
Glaucoma is a multifactorial optic neuropathy characterized by the continuous loss of retinal
ganglion cells, leading to progressive and irreversible visual impairment. In this minireview …
ganglion cells, leading to progressive and irreversible visual impairment. In this minireview …