Early brain injury, an evolving frontier in subarachnoid hemorrhage research

M Fujii, J Yan, WB Rolland, Y Soejima, B Caner… - Translational stroke …, 2013 - Springer
Subarachnoid hemorrhage (SAH), predominantly caused by a ruptured aneurysm, is a
devastating neurological disease that has a morbidity and mortality rate higher than 50 …

[HTML][HTML] Cellular mechanisms of melatonin: insight from neurodegenerative diseases

D Chen, T Zhang, TH Lee - Biomolecules, 2020 - mdpi.com
Neurodegenerative diseases are the second most common cause of death and
characterized by progressive impairments in movement or mental functioning in the central …

Versatile whole-organ/body staining and imaging based on electrolyte-gel properties of biological tissues

EA Susaki, C Shimizu, A Kuno, K Tainaka, X Li… - Nature …, 2020 - nature.com
Whole-organ/body three-dimensional (3D) staining and imaging have been enduring
challenges in histology. By dissecting the complex physicochemical environment of the …

The pathobiology of blast injuries and blast-induced neurotrauma as identified using a new experimental model of injury in mice

I Cernak, AC Merkle, VE Koliatsos, JM Bilik… - Neurobiology of …, 2011 - Elsevier
Current experimental models of blast injuries used to study blast-induced neurotrauma
(BINT) vary widely, which makes the comparison of the experimental results extremely …

Hydrogen-rich saline attenuated subarachnoid hemorrhage-induced early brain injury in rats by suppressing inflammatory response: possible involvement of NF-κB …

A Shao, H Wu, Y Hong, S Tu, X Sun, Q Wu… - Molecular …, 2016 - Springer
Early brain injury (EBI), highlighted with inflammation and apoptosis, occurring within 72 h
after subarachnoid hemorrhage (SAH), is associated with the prognosis of SAH. Recent …

Extracellular matrix and traumatic brain injury

N George, HM Geller - Journal of neuroscience research, 2018 - Wiley Online Library
The brain extracellular matrix (ECM) plays a crucial role in both the develo** and adult
brain by providing structural support and mediating cell‐cell interactions. In this review, we …

The stroke-induced blood-brain barrier disruption: current progress of inspection technique, mechanism, and therapeutic target

T Okada, H Suzuki, ZD Travis… - Current …, 2020 - ingentaconnect.com
Stroke is one of the leading causes of mortality and morbidity worldwide. The bloodbrain
barrier (BBB) is a characteristic structure of microvessel within the brain. Under normal …

A novel role for osteopontin in macrophage-mediated amyloid-β clearance in Alzheimer's models

A Rentsendorj, J Sheyn, DT Fuchs, D Daley… - Brain, behavior, and …, 2018 - Elsevier
Osteopontin (OPN), a matricellular immunomodulatory cytokine highly expressed by
myelomonocytic cells, is known to regulate immune cell migration, communication, and …

[HTML][HTML] Remodeling of the neurovascular unit following cerebral ischemia and hemorrhage

Y Sato, J Falcone-Juengert, T Tominaga, H Su, J Liu - Cells, 2022 - mdpi.com
Formulated as a group effort of the stroke community, the transforming concept of the
neurovascular unit (NVU) depicts the structural and functional relationship between brain …

Transition of research focus from vasospasm to early brain injury after subarachnoid hemorrhage

B Caner, J Hou, O Altay, M Fuj… - Journal of …, 2012 - Wiley Online Library
Subarachnoid hemorrhage is a devastating disease that can be difficult to manage. Not only
is the initial bleeding and rebleeding associated with high mortality, but a large fraction of …