Critical to a sustainable energy future are microbial platforms that can process aromatic
carbons from the largely untapped reservoir of lignin and plastic feedstocks. Comamonas …

Synthetic genomics seeks to design and construct entire genomes to mechanistically dissect
fundamental questions of genome function and to engineer organisms for diverse …

Comamonadaceae bacteria are enriched on poly (ethylene terephthalate)(PET)
microplastics in wastewaters and urban rivers, but the PET-degrading mechanisms remain …

The development of synthetic biological circuits that maintain functionality over application-
relevant time scales remains a significant challenge. Here, we employed synthetic …

Cybergenetics is a new area of research aimed at develo** digital and biological
controllers for living systems. Synthetic biologists have begun exploiting cybergenetic tools …

The increasing demand for bio-based compounds produced from waste or sustainable
sources is driving biofoundries to deliver a new generation of prototy** biomanufacturing …

Designer chromosomes are artificially synthesized chromosomes. Nowadays, these
chromosomes have numerous applications ranging from medical research to the …

Engineering the genetic code of an organism provides the basis for (i) making any organism
safely resistant to natural viruses and (ii) preventing genetic information flow into and out of …

Genetically encoded circuits have been successfully utilized to assess and characterize
target variants with desirable traits from large mutant libraries. Adenosylcobalamin is an …

DNA synthesis serves as the fundamental enabling technology of engineering biology,
aiming to provide DNA molecules of designed composition, length, and complexity at scale …