Emerging diversity in lipid–protein interactions
Membrane lipids interact with proteins in a variety of ways, ranging from providing a stable
membrane environment for proteins to being embedded in to detailed roles in complicated …
membrane environment for proteins to being embedded in to detailed roles in complicated …
Shared molecular mechanisms of membrane transporters
D Drew, O Boudker - Annual review of biochemistry, 2016 - annualreviews.org
The determination of the crystal structures of small-molecule transporters has shed light on
the conformational changes that take place during structural isomerization from outward-to …
the conformational changes that take place during structural isomerization from outward-to …
The role of interfacial lipids in stabilizing membrane protein oligomers
Oligomerization of membrane proteins in response to lipid binding has a critical role in many
cell-signalling pathways but is often difficult to define or predict. Here we report the …
cell-signalling pathways but is often difficult to define or predict. Here we report the …
Architecture and autoinhibitory mechanism of the plasma membrane Na+/H+ antiporter SOS1 in Arabidopsis
Y Wang, C Pan, Q Chen, Q **e, Y Gao, L He… - Nature …, 2023 - nature.com
Abstract Salt-overly-sensitive 1 (SOS1) is a unique electroneutral Na+/H+ antiporter at the
plasma membrane of higher plants and plays a central role in resisting salt stress. SOS1 is …
plasma membrane of higher plants and plays a central role in resisting salt stress. SOS1 is …
Structures and mechanisms of the Arabidopsis auxin transporter PIN3
Abstract The PIN-FORMED (PIN) protein family of auxin transporters mediates polar auxin
transport and has crucial roles in plant growth and development,. Here we present cryo …
transport and has crucial roles in plant growth and development,. Here we present cryo …
[HTML][HTML] The SLC9A-C mammalian Na+/H+ exchanger family: molecules, mechanisms, and physiology
SF Pedersen, L Counillon - Physiological reviews, 2019 - journals.physiology.org
Na+/H+ exchangers play pivotal roles in the control of cell and tissue pH by mediating the
electroneutral exchange of Na+ and H+ across cellular membranes. They belong to an …
electroneutral exchange of Na+ and H+ across cellular membranes. They belong to an …
Structure and mechanism of the human NHE1-CHP1 complex
Y Dong, Y Gao, A Ilie, DS Kim, A Boucher, B Li… - Nature …, 2021 - nature.com
Abstract Sodium/proton exchanger 1 (NHE1) is an electroneutral secondary active
transporter present on the plasma membrane of most mammalian cells and plays critical …
transporter present on the plasma membrane of most mammalian cells and plays critical …
Plant Endomembrane Dynamics: Studies of K+/H+ Antiporters Provide Insights on the Effects of pH and Ion Homeostasis
H Sze, S Chanroj - Plant Physiology, 2018 - academic.oup.com
Plants remodel their cells through the dynamic endomembrane system. Intracellular pH is
important for membrane trafficking, but the determinants of pH homeostasis are poorly …
important for membrane trafficking, but the determinants of pH homeostasis are poorly …
[HTML][HTML] Structure and electromechanical coupling of a voltage-gated Na+/H+ exchanger
Voltage-sensing domains control the activation of voltage-gated ion channels, with a few
exceptions. One such exception is the sperm-specific Na+/H+ exchanger SLC9C1, which is …
exceptions. One such exception is the sperm-specific Na+/H+ exchanger SLC9C1, which is …
Cryo-EM structure of the human neutral amino acid transporter ASCT2
AA Garaeva, GT Oostergetel, C Gati… - Nature structural & …, 2018 - nature.com
Human ASCT2 belongs to the SLC1 family of secondary transporters and is specific for the
transport of small neutral amino acids. ASCT2 is upregulated in cancer cells and serves as …
transport of small neutral amino acids. ASCT2 is upregulated in cancer cells and serves as …