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JASPAR 2022: the 9th release of the open-access database of transcription factor binding profiles
Abstract JASPAR (http://jaspar. genereg. net/) is an open-access database containing
manually curated, non-redundant transcription factor (TF) binding profiles for TFs across six …
manually curated, non-redundant transcription factor (TF) binding profiles for TFs across six …
JASPAR 2020: update of the open-access database of transcription factor binding profiles
Abstract JASPAR (http://jaspar. genereg. net) is an open-access database of curated, non-
redundant transcription factor (TF)-binding profiles stored as position frequency matrices …
redundant transcription factor (TF)-binding profiles stored as position frequency matrices …
A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression
Bidirectional signalling between the tumour and stroma shapes tumour aggressiveness and
metastasis. ATF4 is a major effector of the Integrated Stress Response, a homeostatic …
metastasis. ATF4 is a major effector of the Integrated Stress Response, a homeostatic …
PHOSPHATE STARVATION RESPONSE transcription factors enable arbuscular mycorrhiza symbiosis
Arbuscular mycorrhiza (AM) is a widespread symbiosis between roots of the majority of land
plants and Glomeromycotina fungi. AM is important for ecosystem health and functioning as …
plants and Glomeromycotina fungi. AM is important for ecosystem health and functioning as …
RegulonDB 11.0: Comprehensive high-throughput datasets on transcriptional regulation in Escherichia coli K-12
Genomics has set the basis for a variety of methodologies that produce high-throughput
datasets identifying the different players that define gene regulation, particularly regulation …
datasets identifying the different players that define gene regulation, particularly regulation …
RegulonDB v 10.5: tackling challenges to unify classic and high throughput knowledge of gene regulation in E. coli K-12
RegulonDB, first published 20 years ago, is a comprehensive electronic resource about
regulation of transcription initiation of Escherichia coli K-12 with decades of knowledge from …
regulation of transcription initiation of Escherichia coli K-12 with decades of knowledge from …
Human transcription factor protein interaction networks
H Göös, M Kinnunen, K Salokas, Z Tan, X Liu… - Nature …, 2022 - nature.com
Transcription factors (TFs) interact with several other proteins in the process of
transcriptional regulation. Here, we identify 6703 and 1536 protein–protein interactions for …
transcriptional regulation. Here, we identify 6703 and 1536 protein–protein interactions for …
Acute BAF perturbation causes immediate changes in chromatin accessibility
Abstract Cancer-associated, loss-of-function mutations in genes encoding subunits of the
BRG1/BRM-associated factor (BAF) chromatin-remodeling complexes,,,,,,–often cause …
BRG1/BRM-associated factor (BAF) chromatin-remodeling complexes,,,,,,–often cause …
RSAT 2022: regulatory sequence analysis tools
W Santana-Garcia, JA Castro-Mondragon… - Nucleic Acids …, 2022 - academic.oup.com
Abstract RSAT (Regulatory Sequence Analysis Tools) enables the detection and the
analysis of cis-regulatory elements in genomic sequences. This software suite performs (i) …
analysis of cis-regulatory elements in genomic sequences. This software suite performs (i) …
[HTML][HTML] Opposing functions of BRD4 isoforms in breast cancer
Summary Bromodomain-containing protein 4 (BRD4) is a cancer therapeutic target in
ongoing clinical trials disrupting primarily BRD4-regulated transcription programs. The role …
ongoing clinical trials disrupting primarily BRD4-regulated transcription programs. The role …