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Evolution of genetic mechanisms regulating cortical neurogenesis
A Espinós, E Fernández‐Ortuño… - Developmental …, 2022 - Wiley Online Library
The size of the cerebral cortex increases dramatically across amniotes, from reptiles to great
apes. This is primarily due to different numbers of neurons and glial cells produced during …
apes. This is primarily due to different numbers of neurons and glial cells produced during …
Neocortical neurogenesis in development and evolution—Human‐specific features
WB Huttner, M Heide… - Journal of …, 2024 - Wiley Online Library
In this review, we focus on human‐specific features of neocortical neurogenesis in
development and evolution. Two distinct topics will be addressed. In the first section, we …
development and evolution. Two distinct topics will be addressed. In the first section, we …
Longer metaphase and fewer chromosome segregation errors in modern human than Neanderthal brain development
F Mora-Bermúdez, P Kanis, D Macak, J Peters… - Science …, 2022 - science.org
Since the ancestors of modern humans separated from those of Neanderthals, around 100
amino acid substitutions spread to essentially all modern humans. The biological …
amino acid substitutions spread to essentially all modern humans. The biological …
The evolutionary history of human spindle genes includes back-and-forth gene flow with Neandertals
Proteins associated with the spindle apparatus, a cytoskeletal structure that ensures the
proper segregation of chromosomes during cell division, experienced an unusual number of …
proper segregation of chromosomes during cell division, experienced an unusual number of …
What are the human-specific aspects of neocortex development?
F Mora-Bermúdez, WB Huttner - Frontiers in neuroscience, 2022 - frontiersin.org
When considering what makes us human, the development of the neocortex, the seat of our
higher cognitive abilities, is of central importance. Throughout this complex developmental …
higher cognitive abilities, is of central importance. Throughout this complex developmental …
Corticogenesis and folding process of the neopallium in the South American plains vizcacha, Lagostomus maximus
AR Schmidt, VS Jaime, PIF Inserra… - Journal of …, 2024 - Wiley Online Library
The plains vizcacha, Lagostomus maximus, is a precocial hystricomorph rodent with a
gyrencephalic brain. This work aimed to perform a time‐lapse analysis of the embryonic …
gyrencephalic brain. This work aimed to perform a time‐lapse analysis of the embryonic …
DNA replication fork speed Acts as an Engine in Cortical Neurogenesis
J Wang, Y Kong, X Li, Y Tan, K ** neuroepithelium, as well as the progenitors they
generate, eventually give rise to all the neurons of the mammalian central nervous system …
generate, eventually give rise to all the neurons of the mammalian central nervous system …