The tumorigenic liver fluke Opisthorchis viverrini–multiple pathways to cancer
Liver fluke infection caused by Opisthorchis viverrini is a major public health problem in
Thailand and adjacent countries. In addition to infection-associated morbidity, infection with …
Thailand and adjacent countries. In addition to infection-associated morbidity, infection with …
Liver fluke vaccines in ruminants: strategies, progress and future opportunities
The development of a vaccine for Fasciola spp. in livestock is a challenge and would be
advanced by harnessing our knowledge of acquired immune mechanisms expressed by …
advanced by harnessing our knowledge of acquired immune mechanisms expressed by …
Whole-genome sequence of Schistosoma haematobium
Schistosomiasis is a neglected tropical disease caused by blood flukes (genus
Schistosoma; schistosomes) and affecting 200 million people worldwide. No vaccines are …
Schistosoma; schistosomes) and affecting 200 million people worldwide. No vaccines are …
Liver fluke-associated biliary tract cancer
P Prueksapanich, P Piyachaturawat… - Gut and …, 2017 - pmc.ncbi.nlm.nih.gov
Cholangiocarcinoma (CCA) is an aggressive cancer arising from epithelial cells of the bile
duct. Most patients with CCA have an unresectable tumor at the time of diagnosis. In …
duct. Most patients with CCA have an unresectable tumor at the time of diagnosis. In …
Carcinogenic liver fluke secretes extracellular vesicles that promote cholangiocytes to adopt a tumorigenic phenotype
Abstract Background. Throughout Asia, there is an unprecedented link between
cholangiocarcinoma and infection with the liver fluke Opisthorchis viverrini. Multiple …
cholangiocarcinoma and infection with the liver fluke Opisthorchis viverrini. Multiple …
The Opisthorchis viverrini genome provides insights into life in the bile duct
Opisthorchiasis is a neglected, tropical disease caused by the carcinogenic Asian liver fluke,
Opisthorchis viverrini. This hepatobiliary disease is linked to malignant cancer …
Opisthorchis viverrini. This hepatobiliary disease is linked to malignant cancer …
Non-model organisms, a species endangered by proteogenomics
J Armengaud, J Trapp, O Pible, O Geffard… - Journal of …, 2014 - Elsevier
Previously, large-scale proteomics was possible only for organisms whose genomes were
sequenced, meaning the most common model organisms. The use of next-generation …
sequenced, meaning the most common model organisms. The use of next-generation …
Why does infection with some helminths cause cancer?
Infections with Opisthorchis viverrini, Clonorchis sinensis, and Schistosoma haematobium
are classified as group 1 biological carcinogens: definitive causes of cancer. These worms …
are classified as group 1 biological carcinogens: definitive causes of cancer. These worms …
Proteomic characterisation of Echinococcus granulosus hydatid cyst fluid from sheep, cattle and humans
The hydatid cyst fluid (HCF) of Echinococcus granulosus is a complex biological mixture
containing a wide range of proteins of both parasite and host origin. Using a combination of …
containing a wide range of proteins of both parasite and host origin. Using a combination of …
Recent progress in the development of liver fluke and blood fluke vaccines
DP McManus - Vaccines, 2020 - mdpi.com
Liver flukes (Fasciola spp., Opisthorchis spp., Clonorchis sinensis) and blood flukes
(Schistosoma spp.) are parasitic helminths causing neglected tropical diseases that result in …
(Schistosoma spp.) are parasitic helminths causing neglected tropical diseases that result in …