Advanced glycation end-products (AGEs): Formation, chemistry, classification, receptors, and diseases related to AGEs

A Twarda-Clapa, A Olczak, AM Białkowska… - Cells, 2022 - mdpi.com
Advanced glycation end-products (AGEs) constitute a non-homogenous, chemically diverse
group of compounds formed either exogeneously or endogeneously on the course of …

Mechanism of natural antioxidants regulating advanced glycosylation end products of Maillard reaction

W Jia, A Guo, R Zhang, L Shi - Food Chemistry, 2023 - Elsevier
According to the investigation of Food and Drug Administration 2021, one hundred and
twenty-six potentially harmful substances are produced by Maillard reaction. Discovery of …

Endogenous advanced glycation end products in the pathogenesis of chronic diabetic complications

MA Mengstie, E Chekol Abebe… - Frontiers in molecular …, 2022 - frontiersin.org
Diabetes is a common metabolic illness characterized by hyperglycemia and is linked to
long-term vascular problems that can impair the kidney, eyes, nerves, and blood vessels. By …

[HTML][HTML] Advanced glycation end products and diabetes mellitus: mechanisms and perspectives

M Khalid, G Petroianu, A Adem - Biomolecules, 2022 - mdpi.com
Persistent hyperglycemic state in type 2 diabetes mellitus leads to the initiation and
progression of non-enzymatic glycation reaction with proteins and lipids and nucleic acids …

AGE/RAGE in diabetic kidney disease and ageing kidney

XQ Wu, DD Zhang, YN Wang, YQ Tan, XY Yu… - Free Radical Biology …, 2021 - Elsevier
Diabetic kidney disease (DKD) is the primary cause of chronic kidney disease that inevitably
progress to end-stage kidney disease. Intervention strategies such as blood glucose control …

[HTML][HTML] Advanced glycation end products in health and disease

VP Reddy, P Aryal, EK Darkwah - Microorganisms, 2022 - mdpi.com
Advanced glycation end products (AGEs), formed through the nonenzymatic reaction of
reducing sugars with the side-chain amino groups of lysine or arginine of proteins, followed …

[HTML][HTML] Advanced glycation end products (AGEs) and chronic kidney disease: does the modern diet AGE the kidney?

AK Fotheringham, LA Gallo, DJ Borg, JM Forbes - Nutrients, 2022 - mdpi.com
Since the 1980s, chronic kidney disease (CKD) affecting all ages has increased by almost
25%. This increase may be partially attributable to lifestyle changes and increased global …

Diet's role in modifying risk of Alzheimer's disease: history and present understanding

WB Grant, SM Blake - Journal of Alzheimer's Disease, 2023 - journals.sagepub.com
Diet is an important nonpharmacological risk-modifying factor for Alzheimer's disease (AD).
The approaches used here to assess diet's role in the risk of AD include multi-country …

Chemical stability of proteins in foods: Oxidation and the Maillard reaction

MM Poojary, MN Lund - Annual Review of Food Science and …, 2022 - annualreviews.org
Protein is a major nutrient present in foods along with carbohydrates and lipids. Food
proteins undergo a wide range of modifications during food production, processing, and …

Dietary advanced glycation endproducts (AGEs) increase their concentration in plasma and tissues, result in inflammation and modulate gut microbial composition in …

KCW van Dongen, AMA Linkens, SMW Wetzels… - Food Research …, 2021 - Elsevier
Scope Dietary advanced glycation endproducts (AGEs) are associated with negative
biological effects, possibly due to accumulation in plasma and tissues and through …