Regulated cell death mediated by dedicated molecular machines, known as programmed
cell death, plays important roles in health and disease. Apoptosis, necroptosis and …

This review describes and summarizes the role of neuronal nitric oxide synthase (nNOS) on
the central nervous system, particularly on brain regions such as the ventrolateral medulla …

CHF (chronic heart failure) is a multifactorial disease process that is characterized by
overactivation of the RAAS (renin–angiotensin–aldosterone system) and the sympathetic …

This study aimed to investigate the effect of the sympatholytic drug moxonidine on
atherosclerosis. The effects of moxonidine on oxidised low-density lipoprotein (LDL) uptake …

As a cellular signaling molecule, nitric oxide (NO) is widely conserved from microorganisms,
such as bacteria, yeasts, and fungi, to higher eukaryotes including plants and mammals. NO …

The control of sympathetic outflow in the chronic heart failure (CHF) state is markedly
abnormal. Patients with heart failure present with increased plasma norepinephrine and …

Introduction: Nitric oxide (NO) synthesized via neuronal nitric oxide synthase (nNOS) plays a
significant role in regulation/modulation of autonomic control of circulation. Various …

Hypertension induced by angiotensin II (Ang II) is associated with glutamate-dependent
dysregulation of the hypothalamic paraventricular nucleus (PVN). Many forms of glutamate …

Abstract Glucagon-like peptide-1 receptor (GLP-1R) agonists, widely used to treat type 2
diabetes, reduce blood pressure (BP) in hypertensive patients. Whether this action involves …

Among the members of the mitochondrial carrier family, there are transporters that catalyze
the translocation of ornithine and related substrates, such as arginine, homoarginine, lysine …