Deep brain stimulation for refractory major depressive disorder: a comprehensive review

KA Johnson, MS Okun, KW Scangos, HS Mayberg… - Molecular …, 2024 - nature.com
Deep brain stimulation (DBS) has emerged as a promising treatment for select patients with
refractory major depressive disorder (MDD). The clinical effectiveness of DBS for MDD has …

Deep brain stimulation for treatment-resistant depression: an integrative review of preclinical and clinical findings and translational implications

MP Dandekar, AJ Fenoy, AF Carvalho, JC Soares… - Molecular …, 2018 - nature.com
Although deep brain stimulation (DBS) is an established treatment choice for Parkinson's
disease (PD), essential tremor and movement disorders, its effectiveness for the …

Depression, neuroimaging and connectomics: a selective overview

Q Gong, Y He - Biological psychiatry, 2015 - Elsevier
Depression is a multifactorial disorder with clinically heterogeneous features involving
disturbances of mood and cognitive function. Noninvasive neuroimaging studies have …

[HTML][HTML] Probing and regulating dysfunctional circuits using deep brain stimulation

AM Lozano, N Lipsman - Neuron, 2013 - cell.com
Despite the best available medical treatments, many patients continue to be disabled by
neurologic and psychiatric disorders, resulting in a large unmet need. Advances in imaging …

Where in the brain is depression?

M Pandya, M Altinay, DA Malone, A Anand - Current psychiatry reports, 2012 - Springer
Major depressive disorder is a serious medical illness which is responsible for considerable
morbidity and disability. Despite decades of research, the neural basis for depression is still …

[HTML][HTML] Deep brain stimulation targets for treating depression

D Drobisz, A Damborská - Behavioural brain research, 2019 - Elsevier
Deep brain stimulation (DBS) is a new therapeutic approach for treatment-resistant
depression (TRD). There is a preliminary evidence of the efficacy and safety of DBS for TRD …

The role of adenosine receptors in mood and anxiety disorders

D van Calker, K Biber, K Domschke… - Journal of …, 2019 - Wiley Online Library
Adenosine receptor subtypes, first described 40 years ago, are known to regulate diverse
biological functions and have a role in various conditions, such as cerebral and cardiac …

Microstructural brain abnormalities in medication-free patients with major depressive disorder: a systematic review and meta-analysis of diffusion tensor imaging

J Jiang, YJ Zhao, XY Hu, MY Du, ZQ Chen, M Wu… - Journal of Psychiatry and …, 2017 - jpn.ca
Background: Multiple meta-analyses of diffusion tensor imaging (DTI) studies have reported
impaired white matter integrity in patients with major depressive disorder (MDD). However …

A computational modelling study of transcranial direct current stimulation montages used in depression

S Bai, S Dokos, KA Ho, C Loo - Neuroimage, 2014 - Elsevier
Transcranial direct current stimulation (tDCS) is a neuromodulatory technique which
involves passing a mild electric current to the brain through electrodes placed on the scalp …

[HTML][HTML] Meta-analytic evidence for neuroimaging models of depression: state or trait?

J Graham, G Salimi-Khorshidi, C Hagan… - Journal of affective …, 2013 - Elsevier
Abstract Background Major Depressive Disorder (MDD) is a leading cause of disease
burden worldwide. With the rapid growth of neuroimaging research on relatively small …