Non-celiac gluten sensitivity triggers gut dysbiosis, neuroinflammation, gut-brain axis dysfunction, and vulnerability for dementia

MA Daulatzai - CNS & Neurological Disorders-Drug Targets …, 2015 - ingentaconnect.com
The non-celiac gluten sensitivity (NCGS) is a chronic functional gastrointestinal disorder
which is very common world wide. The human gut harbors microbiota which has a wide …

Central nervous system injury and nicotinamide adenine dinucleotide phosphate oxidase: oxidative stress and therapeutic targets

RE von Leden, YJ Yauger, G Khayrullina… - Journal of …, 2017 - liebertpub.com
Injury to the central nervous system (CNS) includes both traumatic brain and spinal cord
injury (TBI and SCI, respectively). These injuries, which are heterogeneous and, therefore …

Induction of oxidative and nitrosative damage leads to cerebrovascular inflammation in an animal model of mild traumatic brain injury induced by primary blast

PM Abdul-Muneer, H Schuetz, F Wang… - Free Radical Biology …, 2013 - Elsevier
We investigate the hypothesis that oxidative damage of the cerebral vascular barrier
interface (the blood–brain barrier, BBB) causes the development of mild traumatic brain …

Activated microglia are implicated in cognitive deficits, neuronal death, and successful recovery following intermittent ethanol exposure

YN Zhao, F Wang, YX Fan, GF **, JY Yang… - Behavioural brain …, 2013 - Elsevier
Microglia function as the primary immune effector cells in the brain and play a pivotal role in
the neuroinflammatory processes which are critical component of neurodegenerative …

Primary blast causes mild, moderate, severe and lethal TBI with increasing blast overpressures: Experimental rat injury model

V Mishra, M Skotak, H Schuetz, A Heller, J Haorah… - Scientific reports, 2016 - nature.com
Injury severity in blast induced Traumatic Brain Injury (bTBI) increases with blast
overpressure (BOP) and impulse in dose-dependent manner. Pure primary blast waves …

Alcohol-induced oxidative/nitrosative stress alters brain mitochondrial membrane properties

VD Reddy, P Padmavathi, G Kavitha… - Molecular and cellular …, 2013 - Springer
Chronic alcohol consumption causes numerous biochemical and biophysical changes in the
central nervous system, in which mitochondria is the primary organelle affected. In the …

Acetyl-L-carnitine exerts neuroprotective and anticonvulsant effect in kainate murine model of temporal lobe epilepsy

M Tashakori-Miyanroudi, S Ramazi, P Hashemi… - Journal of Molecular …, 2022 - Springer
The most well-known type of focal epilepsy that is resistant to existing treatments is temporal
lobe epilepsy (TLE), with seizure foci in various structures including temporal lobe …

Role of microglia in ethanol-induced neurodegenerative disease: Pathological and behavioral dysfunction at different developmental stages

JY Yang, X Xue, H Tian, XX Wang, YX Dong… - Pharmacology & …, 2014 - Elsevier
Alcohol abuse can result in significant alterations to the structure of the brain and ultimately
to behavioral dysfunctions. Epidemiological studies have shown that alcoholism is closely …

In vivo monitoring of sevoflurane-induced adverse effects in neonatal nonhuman primates using small-animal positron emission tomography

X Zhang, S Liu, GD Newport, MG Paule… - …, 2016 - ingentaconnect.com
Background: Animals exposed to sevoflurane during development sustain neuronal cell
death in their develo** brains. In Vivo micro-positron emission tomography …

Conformational altered p53 as an early marker of oxidative stress in Alzheimer's disease

L Buizza, G Cenini, C Lanni, G Ferrari-Toninelli… - PloS one, 2012 - journals.plos.org
In order to study oxidative stress in peripheral cells of Alzheimer's disease (AD) patients,
immortalized lymphocytes derived from two peculiar cohorts of patients, referring to early …