Proteins started being used as pharmaceuticals in the 1920s with insulin extracted from pig
pancreas. In the early 1980s, human insulin was prepared in recombinant bacteria and it is …

Lentiviral vectors have become a promising new tool for the establishment of transgenic
animals and the manipulation of the mammalian genome. While conventional microinjection …

Genetically modified animals are used for industrial applications as well as scientific
research, and studies on these animals contribute to a better understanding of biological …

Transgenic birds embody one of the most potent and exciting research tools in
biotechnology for agriculture, medicine, and model animals. To date, retrovirus-or lentivirus …

Transgenic chickens could potentially serve as bioreactors for commercial production of
recombinant proteins in egg white. Many transgenic chickens have been generated by …

The recombinant production of therapeutic proteins for human diseases is currently the
largest source of innovation in the pharmaceutical industry. The market growth has been the …

Antibody fragments are used in the clinic as important therapeutic proteins for treatment of
indications where better tissue penetration and less immunogenic molecules are needed …

The outgrowth of the vertebrate tail is thought to involve the proliferation of regionalised
stem/progenitor cell populations formed during gastrulation. To follow these populations …

Transgenic animal bioreactors can produce therapeutic proteins with high value for
pharmaceutical use. In this paper, we compared different systems capable of producing …

CRISPR/Cas9 system genome editing is revolutionizing genetics research in a wide
spectrum of animal models in the genetic era. Among these animals, is the poultry species …