Liquid biopsy at the frontier of detection, prognosis and progression monitoring in colorectal cancer

H Zhou, L Zhu, J Song, G Wang, P Li, W Li, P Luo… - Molecular cancer, 2022 - Springer
Colorectal cancer (CRC) is one of the most common cancers worldwide and a leading
cause of carcinogenic death. To date, surgical resection is regarded as the gold standard by …

From diagnosis to treatment: recent advances in patient-friendly biosensors and implantable devices

P Li, GH Lee, SY Kim, SY Kwon, HR Kim, S Park - ACS nano, 2021 - ACS Publications
Patient-friendly medical diagnostics and treatments have been receiving a great deal of
interest due to their rapid and cost-effective health care applications with minimized risk of …

Precise Capture and Direct Quantification of Tumor Exosomes via a Highly Efficient Dual-Aptamer Recognition-Assisted Ratiometric Immobilization-Free …

L Yang, X Yin, B An, F Li - Analytical Chemistry, 2020 - ACS Publications
Tumor exosomes are promising biomarkers for early cancer diagnosis in a noninvasive
manner. However, precise capture and direct analysis of tumor-specific exosomes in …

Pathogen detection with electrochemical biosensors: Advantages, challenges and future perspectives

HO Kaya, AE Cetin, M Azimzadeh… - Journal of Electroanalytical …, 2021 - Elsevier
Detection of pathogens, eg, bacteria and viruses, is still a big challenge in analytical
medicine due to their vast number and variety. Develo** strategies for rapid, inexpensive …

Integrated lab-on-a-chip devices: Fabrication methodologies, transduction system for sensing purposes

DS Dkhar, R Kumari, SJ Malode, NP Shetti… - … of pharmaceutical and …, 2023 - Elsevier
Abstract Lab-on-a-chip (LOC) biosensors have recently piqued the interest of the research
community as a result of its potential utility in personal healthcare and disease diagnostics …

Simultaneous detection of tumor derived exosomal protein–MicroRNA pairs with an exo-PROS biosensor for cancer diagnosis

CC Hsu, Y Yang, E Kannisto, X Zeng, G Yu… - ACS …, 2023 - ACS Publications
Tumor derived exosomes (TEXs) have emerged as promising biomarkers for cancer liquid
biopsy. Conventional methods (such as ELISA and qRT-PCR) and emerging biosensing …

[HTML][HTML] Biogenesis, isolation, and detection of exosomes and their potential in therapeutics and Diagnostics

S Sonbhadra, Mehak, LM Pandey - Biosensors, 2023 - mdpi.com
The increasing research and rapid developments in the field of exosomes provide insights
into their role and significance in human health. Exosomes derived from various sources …

Exploring the versatility of exosomes: a review on isolation, characterization, detection methods, and diverse applications

O Altıntaş, Y Saylan - Analytical chemistry, 2023 - ACS Publications
Extracellular vesicles (EVs) are crucial mediators of intercellular communication and can be
classified based on their physical properties, biomolecular structure, and origin. Among EVs …

Harnessing tissue-derived extracellular vesicles for osteoarthritis theranostics

B Yin, J Ni, CE Witherel, M Yang, JA Burdick… - …, 2022 - pmc.ncbi.nlm.nih.gov
Osteoarthritis (OA) is a prevalent chronic whole-joint disease characterized by low-grade
systemic inflammation, degeneration of joint-related tissues such as articular cartilage, and …

Nanotechnology-based approaches for effective detection of tumor markers: A comprehensive state-of-the-art review

U Laraib, S Sargazi, A Rahdar, M Khatami… - International journal of …, 2022 - Elsevier
As well-appreciated biomarkers, tumor markers have been spotlighted as reliable tools for
predicting the behavior of different tumors and hel** clinicians ascertain the type of …