Rationally designed antibodies as research tools to study the structure–toxicity relationship of amyloid-β oligomers

R Limbocker, B Mannini, R Cataldi… - International Journal of …, 2020 - mdpi.com
Alzheimer's disease is associated with the aggregation of the amyloid-β peptide (Aβ),
resulting in the deposition of amyloid plaques in brain tissue. Recent scrutiny of the …

Microfluidic Affinity Profiling reveals a Broad Range of Target Affinities for Anti-SARS-CoV-2 Antibodies in Plasma of COVID-19 Survivors

MM Schneider, M Emmenegger, CK Xu, IC Morales… - MedRxiv, 2020 - medrxiv.org
The clinical outcome of SARS-CoV-2 infections can range from asymptomatic to lethal, and
is thought to be crucially shaped by the quality of the immune response which includes …

Kinetic analysis reveals the rates and mechanisms of protein aggregation in a multicellular organism

T Sinnige, G Meisl, TCT Michaels, M Vendruscolo… - bioRxiv, 2020 - biorxiv.org
The accumulation of insoluble protein aggregates containing amyloid fibrils has been
observed in many different human protein misfolding diseases,, and their pathological …