Satellite DNA consists of abundant tandem repeats that play important roles in cellular
processes, including chromosome segregation, genome organization and chromosome end …

Satellite DNA represents one of the most fascinating parts of the repetitive fraction of the
eukaryotic genome. Since the discovery of highly repetitive tandem DNA in the 1960s, a lot …

Existing human genome assemblies have almost entirely excluded repetitive sequences
within and near centromeres, limiting our understanding of their organization, evolution, and …

The complete assembly of each human chromosome is essential for understanding human
biology and evolution,. Here we use complementary long-read sequencing technologies to …

Centromeres are the eukaryotic chromosomal sites at which the kinetochore forms and
attaches to spindle microtubules to orchestrate chromosomal segregation in mitosis and …

There is an increasing interest in detecting genes, or genomic regions, that have been
targeted by natural selection. The interest stems from a basic desire to learn more about …

Chromatin consists of a complex of DNA and histone proteins as its core components and
plays an important role in both packaging DNA and regulating DNA metabolic pathways …

Every eukaryotic chromosome has a centromere, the locus responsible for poleward
movement at mitosis and meiosis. Although conventional loci are specified by their DNA …

Genome data have revealed great variation in the numbers of genes in different organisms,
which indicates that there is a fundamental process of genome evolution: the origin of new …

Genes for which homologs can be detected only in a limited group of evolutionarily related
species, called “lineage-specific genes,” are pervasive: Essentially every lineage has them …