Reactive species are highly-reactive enzymatically, or non-enzymatically produced
compounds with important roles in physiological and pathophysiological cellular processes …

If the atmosphere of the early Earth was hydrogen-rich, 1 it is reasonable to think that
hydrogenases, the enzymes enabling cells to use molecular hydrogen, were probably …

Photosynthetic complex I enables cyclic electron flow around photosystem I, a regulatory
mechanism for photosynthetic energy conversion. We report a 3.3-angstrom-resolution cryo …

Complex I is the first enzyme of the respiratory chain and has a central role in cellular energy
production, coupling electron transfer between NADH and quinone to proton translocation …

Complex I is the first and the largest enzyme of respiratory chains in bacteria and
mitochondria. The mechanism which couples spatially separated transfer of electrons to …

Complex I plays a central role in cellular energy production, coupling electron transfer
between NADH and quinone to proton translocation. The mechanism of this highly efficient …

Friedreich ataxia (FRDA) is a rare, inherited neurodegenerative disease caused by an
expanded GAA repeat in the first intron of the FXN gene, leading to transcriptional silencing …

Kinetic characteristics of the proton-pum** NADH: quinone reductases (respiratory
complexes I) are reviewed. Unsolved problems of the redox-linked proton translocation …

Complex I of respiratory chains plays a central role in cellular energy production. Mutations
in its subunits lead to many human neurodegenerative diseases. Recently, a first atomic …

Complex I (NADH: ubiquinone oxidoreductase) is critical for respiration in mammalian
mitochondria. It oxidizes NADH produced by the Krebs' tricarboxylic acid cycle and β …