Epilepsy and brain network hubs

J Royer, BC Bernhardt, S Larivière, E Gleichgerrcht… - …, 2022 - Wiley Online Library
Epilepsy is a disorder of brain networks. A better understanding of structural and dynamic
network properties may improve epilepsy diagnosis, treatment, and prognostics. Hubs are …

The significance of the default mode network (DMN) in neurological and neuropsychiatric disorders: a review

A Mohan, AJ Roberto, A Mohan… - The Yale journal of …, 2016 - pmc.ncbi.nlm.nih.gov
The relationship of cortical structure and specific neuronal circuitry to global brain function,
particularly its perturbations related to the development and progression of neuropathology …

Regional and global connectivity disturbances in focal epilepsy, related neurocognitive sequelae, and potential mechanistic underpinnings

DJ Englot, PE Konrad, VL Morgan - Epilepsia, 2016 - Wiley Online Library
Epilepsy is among the most common brain network disorders, and it is associated with
substantial morbidity and increased mortality. Although focal epilepsy was traditionally …

Global and regional functional connectivity maps of neural oscillations in focal epilepsy

DJ Englot, LB Hinkley, NS Kort, BS Imber, D Mizuiri… - Brain, 2015 - academic.oup.com
Intractable focal epilepsy is a devastating disorder with profound effects on cognition and
quality of life. Epilepsy surgery can lead to seizure freedom in patients with focal epilepsy; …

Connectomics and graph theory analyses: Novel insights into network abnormalities in epilepsy

E Gleichgerrcht, M Kocher, L Bonilha - Epilepsia, 2015 - Wiley Online Library
The assessment of neural networks in epilepsy has become increasingly relevant in the
context of translational research, given that localized forms of epilepsy are more likely to be …

Deep learning with edge computing for localization of epileptogenicity using multimodal rs-fMRI and EEG big data

MP Hosseini, TX Tran, D Pompili… - 2017 IEEE …, 2017 - ieeexplore.ieee.org
Epilepsy is a chronic brain disorder characterized by the occurrence of spontaneous
seizures of which about 30 percent of patients remain medically intractable and may …

Functional connectivity disturbances of the ascending reticular activating system in temporal lobe epilepsy

DJ Englot, PF D'Haese, PE Konrad… - Journal of Neurology …, 2017 - jnnp.bmj.com
Objective Seizures in temporal lobe epilepsy (TLE) disturb brain networks and lead to
connectivity disturbances. We previously hypothesised that recurrent seizures in TLE may …

Resting-state functional connectivity in epilepsy: growing relevance for clinical decision making

JI Tracy, GE Doucet - Current opinion in neurology, 2015 - journals.lww.com
The role of rsFC remains limited in most clinical settings, but shows great promise for
identifying epileptic circuits and foci, predicting outcomes following surgery, and explaining …

Brain network alteration in patients with temporal lobe epilepsy with cognitive impairment

H Yang, C Zhang, C Liu, T Yu, G Zhang, N Chen… - Epilepsy & Behavior, 2018 - Elsevier
The aims of this study were to investigate the brain network alternation in patients with
temporal lobe epilepsy (TLE) with and without cognitive impairment (CI) using functional …

An analytical workflow for seed-based correlation and independent component analysis in interventional resting-state fMRI studies

BJ Seewoo, AC Joos, KW Feindel - Neuroscience research, 2021 - Elsevier
Resting-state functional MRI (rs-fMRI) is a task-free method of detecting spatially distinct
brain regions with correlated activity, which form organised networks known as resting-state …