A review on recent advances of AI-integrated microfluidics for analytical and bioanalytical applications

E Asadian, F Bahramian, S Siavashy… - TrAC Trends in …, 2024 - Elsevier
In today's biomedical research, the pursuit of diagnostic tools boasting maximum precision
and accuracy while minimizing sample volume and pre-treatment requirements, has …

Autoantibodies immuno-mechanically modulate platelet contractile force and bleeding risk

O Oshinowo, R Copeland, A Patel, N Shaver… - Nature …, 2024 - nature.com
Altered mechanotransduction has been proposed as a putative mechanism for disease
pathophysiology, yet evidence remains scarce. Here we introduce a concept we call single …

Total Synthesis of a PSGL-1 Glycopeptide Analogue for Targeted Inhibition of P-Selectin

B Dhakal, A Mandhapati, P Eradi, S Park… - Journal of the …, 2024 - ACS Publications
The high affinity interaction between P-selectin glycoprotein ligand-1 (PSGL-1) and P-
selectin is mediated by a multimotif glycosulfopeptide (GSP) recognition domain consisting …

A Compact Hydraulic Head Auto-Regulating Module (CHARM) for Long-Term Constant Gravity-Driven Flow Microfluidics

F Xue - 2024 - dspace.mit.edu
Gravity-driven flow is a simple microfluidic flow initiation and maintenance mechanism that
requires no external power sources and low expertise to use. However, the driving forces …

[CITATION][C] Improving healthspan among people with sickle cell disease: Leveraging precision health in an era of treatments with curative intent

EA Yu, HU Zacharias, S Kelly… - American Journal of …, 2024 - Wiley Online Library
With the US Food and Drug Administration (FDA) approval of two new cell-based gene
therapies (Casgevy, Lyfgenia) for sickle cell disease (SCD) on December 8, 2023, 1 gene …