Meniscal injuries caused by trauma, degeneration, osteoarthritis, or other diseases always
result in severe joint pain and motor dysfunction. Due to the unique anatomy of the human …

The meniscus is a key stabilizing tissue of the knee that facilitates proper tracking and
movement of the knee joint and absorbs stresses related to physical activity. This review …

Engineering the meniscus is challenging due to its bizonal structure; the tissue is
cartilaginous at the inner portion and fibrous at the outer portion. Here, we constructed an …

Interface tissue engineering (ITE) is used to repair or regenerate interface living tissue such
as for instance bone and cartilage. This kind of tissues present natural different properties …

A PCL/hydrogel construct that would mimic the structural organization, biochemistry and
anatomy of meniscus was engineered. The compressive (380±40 kPa) and tensile modulus …

Abstract Purpose of Review Lack of vascularity in the human knee meniscus often leads to
surgical removal (total or partial meniscectomy) in the case of severe meniscal damage …

In order to develop scaffold able to mimic the natural gradient properties of tissues, biphasic
and triphasic approaches were adopted. In this work, polycaprolactone/polyethylene glycol …

Ligament, cartilage, and meniscus injuries often have poor healing due to low vascularity
and low proliferative abilities of the resident cells. Drawbacks with conventional treatment …

Here, we investigated the effect of preparation temperature and alginate-coating on L929
fibroblast behavior on lyophilized microporous PLLA/PLGA (95: 5, w/w) scaffolds. The lower …

Menisci are fundamental fibrocartilaginous organs in knee joints. The injury in meniscus can
impair normal knee function and predisposes patients to osteoarthritis. This study prepared …