Cellular immune responses in the pathophysiology of preeclampsia
Preeclampsia, defined as new-onset hypertension accompanied by proteinuria occurring at
20 weeks of gestation or later, is a leading cause of perinatal morbidity and mortality …
20 weeks of gestation or later, is a leading cause of perinatal morbidity and mortality …
Neurodevelopmental outcomes of prenatal preeclampsia exposure
Preeclampsia is a dangerous hypertensive disorder of pregnancy with known links to
negative child health outcomes. Here, we review epidemiological and basic neuroscience …
negative child health outcomes. Here, we review epidemiological and basic neuroscience …
Review of the immune mechanisms of preeclampsia and the potential of immune modulating therapy
YC Ai-ris, LA Smith, SA Karumanchi - Human immunology, 2021 - Elsevier
Successful pregnancy relies on maternal immunologic tolerance mechanisms limit
maladaptive immune responses against the semi-allogeneic fetus and placenta and support …
maladaptive immune responses against the semi-allogeneic fetus and placenta and support …
New immune horizons in therapeutics and diagnostic approaches to Preeclampsia
Hypertensive disorders of pregnancy (HDP) are one of the commonest maladies, affecting
5%–10% of pregnancies worldwide. The American College of Obstetricians and …
5%–10% of pregnancies worldwide. The American College of Obstetricians and …
The serotonin-immune axis in preeclampsia
Abstract Purpose of Review To review the literature and detail the potential immune
mechanisms by which hyperserotonemia may drive pro-inflammation in preeclampsia and to …
mechanisms by which hyperserotonemia may drive pro-inflammation in preeclampsia and to …
Arginine vasopressin infusion is sufficient to model clinical features of preeclampsia in mice
Copeptin, a marker of arginine vasopressin (AVP) secretion, is elevated throughout human
pregnancies complicated by preeclampsia (PE), and AVP infusion throughout gestation is …
pregnancies complicated by preeclampsia (PE), and AVP infusion throughout gestation is …
Animal models of cardiovascular complications of pregnancy
Cardiovascular complications of pregnancy have risen substantially over the past decades,
and now account for the majority of pregnancy-induced maternal deaths, as well as having …
and now account for the majority of pregnancy-induced maternal deaths, as well as having …
Arginine vasopressin and posterior reversible encephalopathy syndrome pathophysiology: the missing link?
B Largeau, O Le Tilly, B Sautenet… - Molecular …, 2019 - Springer
Posterior reversible encephalopathy syndrome (PRES) is a clinicoradiological entity
characterized by a typical brain edema. Its pathogenesis is still debated through …
characterized by a typical brain edema. Its pathogenesis is still debated through …
Chronic maternal interleukin-17 and autism-related cortical gene expression, neurobiology, and behavior
Chronic inflammation during pregnancy (eg, preeclampsia, diabetes) is linked to increased
risk for offspring neurodevelopmental disorders such as autism spectrum disorder (ASD) …
risk for offspring neurodevelopmental disorders such as autism spectrum disorder (ASD) …
Manipulating CD4+ T cell pathways to prevent preeclampsia
Preeclampsia (PreE) is a placental disorder characterized by hypertension (HTN),
proteinuria, and oxidative stress. Individuals with PreE and their children are at an increased …
proteinuria, and oxidative stress. Individuals with PreE and their children are at an increased …