Human leukocyte antigens (HLA) are cell-surface proteins that present peptides to T cells.
These peptides are bound within the peptide binding cleft of HLA, and together as a …

Human leukocyte antigen (HLA) can recognize and bind foreign peptides to present them to
specialized immune cells, then initiate an immune response. Computational prediction of the …

ABSTRACT The Immune Epitope Database (IEDB, www. iedb. org) provides a catalog of
experimentally characterized B and T cell epitopes, as well as data on Major …

Cancer immunoinformatics have led to new directions towards vaccine design from
predicted potential epitope candidates, which are able to stimulate the correct cellular or …

AntiJen is a database system focused on the integration of kinetic, thermodynamic,
functional, and cellular data within the context of immunology and vaccinology. Compared to …

Background Peptides are important molecules with diverse biological functions and
biomedical uses. To date, there does not exist a single, searchable archive for peptide …

In this article, we present a new technique for the rapid and precise docking of peptides to
MHC class I and class II receptors. Our docking procedure consists of three steps:(1) peptide …

The binding groove of class I major histocompatibility complex (MHC) class is essentially
important for antigen binding and presentation on T cells. There are several molecules that …

Major histocompatibility complex (MHC) possesses important research value in the
treatment of complex human diseases. A plethora of computational tools has been …

Attempts to develop peptide vaccines, based on a limited number of peptides face two
problems: HLA polymorphism and the high mutation rate of viral epitopes. We have …