Inflammatory mechanisms in patients with chronic obstructive pulmonary disease

PJ Barnes - Journal of Allergy and Clinical Immunology, 2016 - Elsevier
Chronic obstructive pulmonary disease (COPD) is associated with chronic inflammation
affecting predominantly the lung parenchyma and peripheral airways that results in largely …

Update on clinical aspects of chronic obstructive pulmonary disease

BR Celli, JA Wedzicha - New England Journal of Medicine, 2019 - Mass Medical Soc
Update on Clinical Aspects of Chronic Obstructive Pulmonary Disease | New England Journal of
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

Comparison of World Health Organization and Asia-Pacific body mass index classifications in COPD patients

JU Lim, JH Lee, JS Kim, YI Hwang, TH Kim… - … journal of chronic …, 2017 - Taylor & Francis
Introduction A low body mass index (BMI) is associated with increased mortality and low
health-related quality of life in patients with COPD. The Asia-Pacific classification of BMI has …

Cellular and molecular mechanisms of asthma and COPD

PJ Barnes - Clinical science, 2017 - portlandpress.com
Asthma and chronic obstructive pulmonary disease (COPD) both cause airway obstruction
and are associated with chronic inflammation of the airways. However, the nature and sites …

Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations

P Sakornsakolpat, D Prokopenko, M Lamontagne… - Nature …, 2019 - nature.com
Chronic obstructive pulmonary disease (COPD) is the leading cause of respiratory mortality
worldwide. Genetic risk loci provide new insights into disease pathogenesis. We performed …

COPD and multimorbidity: recognising and addressing a syndemic occurrence

LM Fabbri, BR Celli, A Agustí, GJ Criner… - The Lancet …, 2023 - thelancet.com
Most patients with chronic obstructive pulmonary disease (COPD) have at least one
additional, clinically relevant chronic disease. Those with the most severe airflow obstruction …

Distinct subtypes of polycystic ovary syndrome with novel genetic associations: An unsupervised, phenotypic clustering analysis

M Dapas, FTJ Lin, GN Nadkarni, R Sisk, RS Legro… - PLoS …, 2020 - journals.plos.org
Background Polycystic ovary syndrome (PCOS) is a common, complex genetic disorder
affecting up to 15% of reproductive-age women worldwide, depending on the diagnostic …

Inflammatory endotypes in COPD

PJ Barnes - Allergy, 2019 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) is a major global health problem that is
poorly treated by current therapies as it has proved difficult to treat the underlying …

[HTML][HTML] Pathobiological mechanisms underlying metabolic syndrome (MetS) in chronic obstructive pulmonary disease (COPD): clinical significance and therapeutic …

SMH Chan, S Selemidis, S Bozinovski… - Pharmacology & …, 2019 - Elsevier
Chronic obstructive pulmonary disease (COPD) is a major incurable global health burden
and is currently the 4th largest cause of death in the world. Importantly, much of the disease …

[HTML][HTML] Artificial intelligence and machine learning in chronic airway diseases: focus on asthma and chronic obstructive pulmonary disease

Y Feng, Y Wang, C Zeng, H Mao - International journal of medical …, 2021 - ncbi.nlm.nih.gov
Chronic airway diseases are characterized by airway inflammation, obstruction, and
remodeling and show high prevalence, especially in develo** countries. Among them …