The integrin “very late antigen-4”(VLA-4) is expressed by numerous cells of hematopoietic
origin and possesses a key function in the cellular immune response, eg, by mediating …

The very late activation antigens (VLA) or β1 integrins mediate cell attachment to different
extracellular matrix proteins and intercellular adhesions. The ligand binding activity of these …

The main function of platelets is to maintain normal hemostasis. Inefficient platelet
production and/or defective platelet function results in bleeding disorders resulting from a …

Peritoneal dissemination is a frequent metastatic route for cancers of the ovary and
gastrointestinal tract. Tumour cells metastasize by attaching to and invading through the …

Cell-to-cell junction structures play a key role in cell growth rate control and cell polarization.
In endothelial cells (EC), these structures are also involved in regulation of vascular …

Among a series of adhesion molecules, expression of integrin a461 showed a unique
inverse correlation with the invasive potential of B16 melanoma cell lines. When an a4 …

We have characterized the immunobiology of the interaction of intercellular adhesion
molecule 3 (ICAM-3; CD50) with its counter-receptor, leukocyte function-associated antigen …

The interaction of lymphocyte function-associated antigen-1 (LFA-1) with its ligands
mediates multiple cell adhesion processes of capital importance during immune responses …

Colorectal cancer (CRC) and ovarian cancer (OvC) patients frequently develop peritoneal
metastasis, a condition associated with a very poor prognosis. In these cancers, tumor …

The implication of the tetraspanin CD9 in cancer has received much recent attention and an
inverse correlation between CD9 expression and the metastatic potential and cancer …