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Chitosan-based nanomaterials for drug delivery
This review discusses different forms of nanomaterials generated from chitosan and its
derivatives for controlled drug delivery. Nanomaterials are drug carriers with multiple …
derivatives for controlled drug delivery. Nanomaterials are drug carriers with multiple …
Metal nanoclusters: novel probes for diagnostic and therapeutic applications
Y Tao, M Li, J Ren, X Qu - Chemical Society Reviews, 2015 - pubs.rsc.org
Metal nanoclusters, composed of several to a few hundred metal atoms, have received
worldwide attention due to their extraordinary physical and chemical characteristics …
worldwide attention due to their extraordinary physical and chemical characteristics …
Synthetic polypeptides: from polymer design to supramolecular assembly and biomedical application
Synthetic polypeptides from the ring-opening polymerization of N-carboxyanhydrides
(NCAs) are one of the most important biomaterials. The unique features of these synthetic …
(NCAs) are one of the most important biomaterials. The unique features of these synthetic …
Nonviral gene editing via CRISPR/Cas9 delivery by membrane-disruptive and endosomolytic helical polypeptide
Effective and safe delivery of the CRISPR/Cas9 gene-editing elements remains a challenge.
Here we report the development of PEGylated nanoparticles (named P-HNPs) based on the …
Here we report the development of PEGylated nanoparticles (named P-HNPs) based on the …
Actively targeted nanomedicines for precision cancer therapy: Concept, construction, challenges and clinical translation
The development of targeted nanomedicines for cancer therapy has been an utmost focus of
research across different fields including materials science, nanotechnology, biotechnology …
research across different fields including materials science, nanotechnology, biotechnology …
Functional supramolecular polymers for biomedical applications
As a novel class of dynamic and non‐covalent polymers, supramolecular polymers not only
display specific structural and physicochemical properties, but also have the ability to …
display specific structural and physicochemical properties, but also have the ability to …
Injectable graphene oxide/hydrogel-based angiogenic gene delivery system for vasculogenesis and cardiac repair
The objective of this study was to develop an injectable and biocompatible hydrogel which
can efficiently deliver a nanocomplex of graphene oxide (GO) and vascular endothelial …
can efficiently deliver a nanocomplex of graphene oxide (GO) and vascular endothelial …
A review of chitosan in gene therapy: developments and challenges
L Dong, Y Li, H Cong, B Yu, Y Shen - Carbohydrate Polymers, 2024 - Elsevier
Gene therapy, as a revolutionary treatment, has been gaining more and more attention. The
key to gene therapy is the selection of suitable vectors for protection of exogenous nucleic …
key to gene therapy is the selection of suitable vectors for protection of exogenous nucleic …
Tumor acidity-sensitive polymeric vector for active targeted siRNA delivery
Although surface PEGylation of siRNA vectors is effective for preventing protein adsorption
and thereby helps these vectors to evade the reticuloendothelial system (RES) in vivo, it also …
and thereby helps these vectors to evade the reticuloendothelial system (RES) in vivo, it also …
Functional polypeptide and hybrid materials: Precision synthesis via α-amino acid N-carboxyanhydride polymerization and emerging biomedical applications
Polypeptides derived from naturally occurring α-amino acids have emerged as a unique and
versatile family of bio-inspired biomaterials that can be tailor-made for varying biomedical …
versatile family of bio-inspired biomaterials that can be tailor-made for varying biomedical …