Bioadhesive technology platforms

SJ Wu, X Zhao - Chemical Reviews, 2023 - ACS Publications
Bioadhesives have emerged as transformative and versatile tools in healthcare, offering the
ability to attach tissues with ease and minimal damage. These materials present numerous …

Biophysics in tumor growth and progression: from single mechano-sensitive molecules to mechanomedicine

Y **n, K Li, M Huang, C Liang, D Siemann, L Wu, Y Tan… - Oncogene, 2023 - nature.com
Evidence from physical sciences in oncology increasingly suggests that the interplay
between the biophysical tumor microenvironment and genetic regulation has significant …

The gut microbiota promotes distal tissue regeneration via RORγ+ regulatory T cell emissaries

BS Hanna, G Wang, S Galván-Peña, AO Mann… - Immunity, 2023 - cell.com
Specific microbial signals induce the differentiation of a distinct pool of RORγ+ regulatory T
(Treg) cells crucial for intestinal homeostasis. We discovered highly analogous populations …

Active tissue adhesive activates mechanosensors and prevents muscle atrophy

S Nam, BR Seo, AJ Najibi, SL McNamara… - Nature materials, 2023 - nature.com
While mechanical stimulation is known to regulate a wide range of biological processes at
the cellular and tissue levels, its medical use for tissue regeneration and rehabilitation has …

[HTML][HTML] Fusobacterium nucleatum aggravates rheumatoid arthritis through FadA-containing outer membrane vesicles

M Hong, Z Li, H Liu, S Zheng, F Zhang, J Zhu, H Shi… - Cell Host & Microbe, 2023 - cell.com
Rheumatoid arthritis (RA) is an autoimmune disorder that has been associated with the gut
microbiota. However, whether and how the gut microbiota plays a pathogenic role in RA …

Wearable and Implantable Soft Robots

S Yin, DR Yao, Y Song, W Heng, X Ma, H Han… - Chemical …, 2024 - ACS Publications
Soft robotics presents innovative solutions across different scales. The flexibility and
mechanical characteristics of soft robots make them particularly appealing for wearable and …

3D printing of self‐assembling nanofibrous multidomain peptide hydrogels

AC Farsheed, AJ Thomas, BH Pogostin… - Advanced …, 2023 - Wiley Online Library
Abstract 3D printing has become one of the primary fabrication strategies used in biomedical
research. Recent efforts have focused on the 3D printing of hydrogels to create structures …

Soft robot–mediated autonomous adaptation to fibrotic capsule formation for improved drug delivery

R Beatty, KL Mendez, LHJ Schreiber, R Tarpey… - Science Robotics, 2023 - science.org
The foreign body response impedes the function and longevity of implantable drug delivery
devices. As a dense fibrotic capsule forms, integration of the device with the host tissue …

A discrete 'early-responder'stromal-cell subtype orchestrates immunocyte recruitment to injured tissue

OK Yaghi, BS Hanna, PK Langston, DA Michelson… - Nature …, 2023 - nature.com
Following acute injury, stromal cells promote tissue regeneration by a diversity of
mechanisms. Time-resolved single-cell RNA sequencing of muscle mesenchymal stromal …

Platelet-derived chemokines promote skeletal muscle regeneration by guiding neutrophil recruitment to injured muscles

FA Graca, A Stephan, BA Minden-Birkenmaier… - Nature …, 2023 - nature.com
Skeletal muscle regeneration involves coordinated interactions between different cell types.
Injection of platelet-rich plasma is circumstantially considered an aid to muscle repair but …