Alzheimer's disease treatment: the search for a breakthrough
AB Reiss, D Muhieddine, B Jacob, M Mesbah… - Medicina, 2023 - mdpi.com
As the search for modalities to cure Alzheimer's disease (AD) has made slow progress,
research has now turned to innovative pathways involving neural and peripheral …
research has now turned to innovative pathways involving neural and peripheral …
Huntington's disease: complex pathogenesis and therapeutic strategies
H Tong, T Yang, S Xu, X Li, L Liu, G Zhou… - International Journal of …, 2024 - mdpi.com
Huntington's disease (HD) arises from the abnormal expansion of CAG repeats in the
huntingtin gene (HTT), resulting in the production of the mutant huntingtin protein (mHTT) …
huntingtin gene (HTT), resulting in the production of the mutant huntingtin protein (mHTT) …
[HTML][HTML] Antisense oligonucleotides-based approaches for the treatment of multiple myeloma
Multiple myeloma (MM), a hematological malignancy which affects the monoclonal plasma
cells in the bone marrow, is in rising incidence around the world, accounting for …
cells in the bone marrow, is in rising incidence around the world, accounting for …
Advances in carrier-delivered small interfering RNA based therapeutics for treatment of neurodegenerative diseases
W Liang, Y Luo, A Xu, J Chu, W Ji, L Wang, Y Gu… - Biomaterials …, 2024 - pubs.rsc.org
Neurodegenerative disease are devastating diseases that severely affected the health of
people all over the world. RNA therapies have become one of the most promising critical …
people all over the world. RNA therapies have become one of the most promising critical …
New insights into polysaccharide-based nanostructured delivery systems in breast cancer: Possible application of antisense oligonucleotides in breast cancer therapy
F Shayegh, Z Turk, A Fejzullahu, N Zarghami - International Journal of …, 2024 - Elsevier
The lack of more effective therapies for breast cancer has enhanced mortality among breast
cancer patients. Recent efforts have established efficient treatments to reduce breast cancer …
cancer patients. Recent efforts have established efficient treatments to reduce breast cancer …
Structure-activity relationship of modified amphiphilic cationic cyclodextrins for enhanced siRNA delivery
The presence of multiple hydroxyl groups at positions C2, C3 and C6 on the cyclodextrin
(CD) ring structure allows for extensive functionalisation, enabling the development of …
(CD) ring structure allows for extensive functionalisation, enabling the development of …
Advancing CNS Therapeutics: Enhancing Neurological Disorders with Nanoparticle-Based Gene and Enzyme Replacement Therapies
S Liu, H Li, S **, Y Zhang, T Sun - International Journal of …, 2025 - Taylor & Francis
Given the complexity of the central nervous system (CNS) and the diversity of neurological
conditions, the increasing prevalence of neurological disorders poses a significant …
conditions, the increasing prevalence of neurological disorders poses a significant …
[HTML][HTML] Cyclodextrin-Containing Drug Delivery Systems and Their Applications in Neurodegenerative Disorders
Y **ng, B Meng, Q Chen - International Journal of Molecular Sciences, 2024 - mdpi.com
Cyclodextrins (CDs) are ubiquitous excipients, constituted of cyclic glucopyranose units, and
possess a unique dual nature, that of a hydrophobic interior and a hydrophilic exterior. This …
possess a unique dual nature, that of a hydrophobic interior and a hydrophilic exterior. This …
Innovation in nanomedicine: nanocarriers for central nervous system disorders management
MA Waqar, N Mubarak, AM Khan… - … Journal of Polymeric …, 2024 - Taylor & Francis
Abstract Rising prevalence of Central Nervous System (CNS) illnesses poses an issue of
concern for global health, requiring new and innovative treatment approaches. Current …
concern for global health, requiring new and innovative treatment approaches. Current …