An unprecedented revolution in medicinal chemistry driven by the progress of biological science
KC Chou - Current topics in medicinal chemistry, 2017 - ingentaconnect.com
The eternal or ultimate goal of medicinal chemistry is to find most effective ways to treat
various diseases and extend human beings' life as long as possible. Human being is a …
various diseases and extend human beings' life as long as possible. Human being is a …
Pseudo nucleotide composition or PseKNC: an effective formulation for analyzing genomic sequences
With the avalanche of DNA/RNA sequences generated in the post-genomic age, it is urgent
to develop automated methods for analyzing the relationship between the sequences and …
to develop automated methods for analyzing the relationship between the sequences and …
[HTML][HTML] Pse-in-One 2.0: an improved package of web servers for generating various modes of pseudo components of DNA, RNA, and protein sequences
B Liu, H Wu, KC Chou - Natural science, 2017 - scirp.org
Pse-in-One 2.0 is a package of web-servers evolved from Pse-in-One (Liu, B., Liu, F., Wang,
X., Chen, J. Fang, L. & Chou, KC Nucleic Acids Research, 2015, 43: W65-W71). In order to …
X., Chen, J. Fang, L. & Chou, KC Nucleic Acids Research, 2015, 43: W65-W71). In order to …
PseAAC-General: fast building various modes of general form of Chou's pseudo-amino acid composition for large-scale protein datasets
P Du, S Gu, Y Jiao - International journal of molecular sciences, 2014 - mdpi.com
The general form pseudo-amino acid composition (PseAAC) has been widely used to
represent protein sequences in predicting protein structural and functional attributes. We …
represent protein sequences in predicting protein structural and functional attributes. We …
pLoc_bal-mAnimal: predict subcellular localization of animal proteins by balancing training dataset and PseAAC
Progresses in predicting post-translational modification
KC Chou - International Journal of Peptide Research and …, 2020 - Springer
Identification of the sites of post-translational modifications (PTMs) in protein, RNA, and DNA
sequences is currently a very hot topic. This is because the information thus obtained is very …
sequences is currently a very hot topic. This is because the information thus obtained is very …
Recent progress in predicting posttranslational modification sites in proteins
Y Xu, KC Chou - Current topics in medicinal chemistry, 2016 - ingentaconnect.com
The posttranslational modification or PTM is a later but subtle step in protein biosynthesis via
which to change the properties of a protein by adding a modified group to its one or more …
which to change the properties of a protein by adding a modified group to its one or more …
pLoc_bal-mGneg: Predict subcellular localization of Gram-negative bacterial proteins by quasi-balancing training dataset and general PseAAC
X Cheng, X **ao, KC Chou - Journal of theoretical biology, 2018 - Elsevier
One of the hottest topics in molecular cell biology is to determine the subcellular localization
of proteins from various different organisms. This is because it is crucially important for both …
of proteins from various different organisms. This is because it is crucially important for both …
[HTML][HTML] pLoc_bal-mHum: predict subcellular localization of human proteins by PseAAC and quasi-balancing training dataset
KC Chou, X Cheng, X **ao - Genomics, 2019 - Elsevier
A cell contains numerous protein molecules. One of the fundamental goals in molecular cell
biology is to determine their subcellular locations since this information is extremely …
biology is to determine their subcellular locations since this information is extremely …