Functional connectivity of the brain across rodents and humans

N Xu, TJ LaGrow, N Anumba, A Lee, X Zhang… - Frontiers in …, 2022 - frontiersin.org
Resting-state functional magnetic resonance imaging (rs-fMRI), which measures the
spontaneous fluctuations in the blood oxygen level-dependent (BOLD) signal, is …

A consensus protocol for functional connectivity analysis in the rat brain

J Grandjean, G Desrosiers-Gregoire, C Anckaerts… - Nature …, 2023 - nature.com
Task-free functional connectivity in animal models provides an experimental framework to
examine connectivity phenomena under controlled conditions and allows for comparisons …

An App knock-in rat model for Alzheimer's disease exhibiting Aβ and tau pathologies, neuronal death and cognitive impairments

K Pang, R Jiang, W Zhang, Z Yang, LL Li… - Cell research, 2022 - nature.com
A major obstacle in Alzheimer's disease (AD) research is the lack of predictive and
translatable animal models that reflect disease progression and drug efficacy. Transgenic …

Waxholm Space atlas of the rat brain: A 3D atlas supporting data analysis and integration

H Kleven, IE Bjerke, F Clascá, HJ Groenewegen… - Nature …, 2023 - nature.com
Volumetric brain atlases are increasingly used to integrate and analyze diverse
experimental neuroscience data acquired from animal models, but until recently a publicly …

fMRI data acquisition and analysis for task-free, anesthetized rats

RM Vrooman, M van den Berg… - Nature protocols, 2025 - nature.com
Templates for the acquisition of large datasets such as the Human Connectome Project
guide the neuroimaging community to reproducible data acquisition and scientific rigor. By …

Dopamine transporter silencing in the rat: systems-level alterations in striato-cerebellar and prefrontal-midbrain circuits

JR Reinwald, N Gass, AS Mallien, A Sartorius… - Molecular …, 2022 - nature.com
Silencing of dopamine transporter (DAT), a main controlling factor of dopaminergic
signaling, results in biochemical and behavioral features characteristic for neuropsychiatric …

Modeling the early stages of Alzheimer's disease by administering intracerebroventricular injections of human native Aβ oligomers to rats

E Baerends, K Soud, J Folke, AK Pedersen… - Acta neuropathologica …, 2022 - Springer
Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disease
characterized by the accumulation of aggregated amyloid beta (Aβ) and …

FUS-mediated BBB opening leads to transient perfusion decrease and inflammation without acute or chronic brain lesion

S Rigollet, C Rome, T Ador, E Dumont, C Pichon… - …, 2024 - pmc.ncbi.nlm.nih.gov
Impact: The permeabilization of the BBB to deliver therapeutics with MR-guided FUS
redefines therapeutic strategies as it improves patient outcomes. To ensure the best …

[HTML][HTML] An open database of resting-state fMRI in awake rats

Y Liu, PD Perez, Z Ma, Z Ma, D Dopfel, S Cramer, W Tu… - NeuroImage, 2020 - Elsevier
Rodent models are essential to translational research in health and disease. Investigation in
rodent brain function and organization at the systems level using resting-state functional …

Diffusion tensor imaging and plasma immunological biomarker panel in a rat traumatic brain injury (TBI) model and in human clinical TBI

XV To, AZ Mohamed, P Cumming… - Frontiers in …, 2024 - frontiersin.org
Introduction Neuroinflammatory reactions play a significant role in the pathology and long-
term consequences of traumatic brain injury (TBI) and may mediate salutogenic processes …