In terms of the number and diversity of living units, the prokaryotic empire is the most
represented form of life on Earth, and yet it is still to a significant degree shrouded in …

Actinobacteria constitute prolific sources of novel and vital bioactive metabolites for
pharmaceutical utilization. In recent years, research has focused on exploring actinobacteria …

Caves are typified by their permanent darkness and a shortage of nutrients. Consequently,
bacteria play an important role in sustaining such subsurface ecosystems by dominating …

Recently, there is an urgent need for new drugs due to the emergence of drug resistant
pathogenic microorganisms and new infectious diseases. Members of phylum …

Microbial natural products have been one of the most important sources for the discovery of
potential new antibiotics. However, the decline in the number of new chemical scaffolds …

Caves have been an item of amateur and professional exploration for many years. Research
on the karst caves has revealed great diversity of bacteria, algae, and fungi living on stone …

Actinomycetes are well known as an inexhaustible source for antibiotics. Most of the known
antimicrobials today were originally isolated from actinomycetes, especially from the genus …

Resistance of bacteria, fungi and cancer cells to antibiotics and other drugs is recognized as
one of the major problems in current medicine. Therefore, a search for new biologically …

Rhizosphere and root-associated bacteria are key components of crop production and
sustainable agriculture. However, utilization of these beneficial bacteria is often limited by …

Among fundamental research questions in subterranean biology, the role of subterranean
microbiomes playing in key elements cycling is a top-priority one. Karst caves are widely …