Genetic coding variants in APOL1, which encodes apolipoprotein L1 (APOL1), were
identified in 2010 and are relatively common among individuals of sub-Saharan African …

Suramin is 100 years old and is still being used to treat the first stage of acute human
slee** sickness, caused by Trypanosoma brucei rhodesiense. Suramin is a …

Human African Trypanosomiasis (HAT, slee** sickness) and Animal African
Trypanosomiasis (AAT) are neglected tropical diseases generally caused by the same …

African trypanosomiasis is associated with Trypanosoma evansi, T. vivax, T. congolense,
and T. brucei pathogens in African animal trypanosomiasis (AAT) while T. b gambiense and …

Salivarian trypanosomes are single cell extracellular parasites that cause infections in a
wide range of hosts. Most pathogenic infections worldwide are caused by one of four major …

Human trypanosomiasis and leishmaniasis are vector‐borne neglected tropical diseases
caused by infection with the protozoan parasites Trypanosoma spp. and Leishmania spp …

African trypanosomes cause lethal and neglected tropical diseases, known as slee**
sickness in humans and nagana in animals. Current therapies are limited, but fortunately …

African slee** sickness, Chagas disease, and leishmaniasis are life-threatening diseases
that together affect millions of people around the world and are caused by different members …

Developmental steps in the trypanosome life-cycle involve transition between replicative
and non-replicative forms specialised for survival in, and transmission between, mammalian …

Intestinal parasitic nematodes infect approximately two billion people worldwide. In the
absence of vaccines for human intestinal nematodes, control of infections currently relies …