The evolving story of apolipoprotein L1 nephropathy: the end of the beginning
Genetic coding variants in APOL1, which encodes apolipoprotein L1 (APOL1), were
identified in 2010 and are relatively common among individuals of sub-Saharan African …
identified in 2010 and are relatively common among individuals of sub-Saharan African …
100 years of suramin
N Wiedemar, DA Hauser, P Mäser - Antimicrobial agents and …, 2020 - Am Soc Microbiol
Suramin is 100 years old and is still being used to treat the first stage of acute human
slee** sickness, caused by Trypanosoma brucei rhodesiense. Suramin is a …
slee** sickness, caused by Trypanosoma brucei rhodesiense. Suramin is a …
An update on African trypanocide pharmaceutics and resistance
African trypanosomiasis is associated with Trypanosoma evansi, T. vivax, T. congolense,
and T. brucei pathogens in African animal trypanosomiasis (AAT) while T. b gambiense and …
and T. brucei pathogens in African animal trypanosomiasis (AAT) while T. b gambiense and …
Current treatments to control African trypanosomiasis and one health perspective
A Venturelli, L Tagliazucchi, C Lima, F Venuti… - Microorganisms, 2022 - mdpi.com
Human African Trypanosomiasis (HAT, slee** sickness) and Animal African
Trypanosomiasis (AAT) are neglected tropical diseases generally caused by the same …
Trypanosomiasis (AAT) are neglected tropical diseases generally caused by the same …
Parasitic diseases of equids in Iran (1931–2020): a literature review
Parasitic infections can cause many respiratory, digestive and other diseases and contribute
to some performance conditions in equids. However, knowledge on the biodiversity of …
to some performance conditions in equids. However, knowledge on the biodiversity of …
Salivarian trypanosomosis: a review of parasites involved, their global distribution and their interaction with the innate and adaptive mammalian host immune system
M Radwanska, N Vereecke, V Deleeuw… - Frontiers in …, 2018 - frontiersin.org
Salivarian trypanosomes are single cell extracellular parasites that cause infections in a
wide range of hosts. Most pathogenic infections worldwide are caused by one of four major …
wide range of hosts. Most pathogenic infections worldwide are caused by one of four major …
Clinical and veterinary trypanocidal benzoxaboroles target CPSF3
RJ Wall, E Rico, I Lukac, F Zuccotto… - Proceedings of the …, 2018 - National Acad Sciences
African trypanosomes cause lethal and neglected tropical diseases, known as slee**
sickness in humans and nagana in animals. Current therapies are limited, but fortunately …
sickness in humans and nagana in animals. Current therapies are limited, but fortunately …
Single-cell transcriptomic analysis of bloodstream Trypanosoma brucei reconstructs cell cycle progression and developmental quorum sensing
Developmental steps in the trypanosome life-cycle involve transition between replicative
and non-replicative forms specialised for survival in, and transmission between, mammalian …
and non-replicative forms specialised for survival in, and transmission between, mammalian …
The current drug discovery landscape for trypanosomiasis and leishmaniasis: Challenges and strategies to identify drug targets
F Altamura, R Rajesh, CMC Catta‐Preta… - Drug development …, 2022 - Wiley Online Library
Human trypanosomiasis and leishmaniasis are vector‐borne neglected tropical diseases
caused by infection with the protozoan parasites Trypanosoma spp. and Leishmania spp …
caused by infection with the protozoan parasites Trypanosoma spp. and Leishmania spp …
Plant-based natural products for the discovery and development of novel anthelmintics against nematodes
Intestinal parasitic nematodes infect approximately two billion people worldwide. In the
absence of vaccines for human intestinal nematodes, control of infections currently relies …
absence of vaccines for human intestinal nematodes, control of infections currently relies …