Evolving SAXS versatility: solution X-ray scattering for macromolecular architecture, functional landscapes, and integrative structural biology
CA Brosey, JA Tainer - Current opinion in structural biology, 2019 - Elsevier
Highlights•SAXS captures architecture and dynamics to elucidate molecular
ensembles.•SAXS advances now probe key thermodynamic and kinetic properties of …
ensembles.•SAXS advances now probe key thermodynamic and kinetic properties of …
Unfolding the mysteries of protein metamorphosis
Since the proposal of Anfinsen's thermodynamic hypothesis in 1963, our understanding of
protein folding and dynamics has gained significant appreciation of its nuance and …
protein folding and dynamics has gained significant appreciation of its nuance and …
Mechanistic insights into IscU conformation regulation for Fe–S cluster biogenesis revealed by variable temperature electrospray ionization native ion mobility mass …
CW Lin, SD Oney-Hawthorne, ST Kuo… - Biochemistry, 2022 - ACS Publications
Iron–sulfur (Fe–S) cluster (ISC) cofactors are required for the function of many critical cellular
processes. In the ISC Fe–S cluster biosynthetic pathway, IscU assembles Fe–S cluster …
processes. In the ISC Fe–S cluster biosynthetic pathway, IscU assembles Fe–S cluster …
A folding reaction at the C-terminal domain drives temperature sensing in TRPM8 channels
In mammals, temperature-sensitive TRP channels make membrane conductance of cells
extremely temperature dependent, allowing the detection of temperature ranging from …
extremely temperature dependent, allowing the detection of temperature ranging from …
The cold denaturation of IscU highlights structure–function dualism in marginally stable proteins
R Yan, P DeLos Rios, A Pastore… - Communications …, 2018 - nature.com
Proteins undergo both cold and heat denaturation, but often cold denaturation cannot be
detected because it occurs at temperatures below water freezing. Proteins undergoing …
detected because it occurs at temperatures below water freezing. Proteins undergoing …
[HTML][HTML] The favored mechanism for co** with acute cold stress: upregulation of miR-210 in rats
W Guo, S Lian, L Zhen, S Zang, Y Chen… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: The main aim of this study was to determine the mechanisms by which
rno-miR-210-3p affects changes in gene expression, metabolism, apoptosis and …
rno-miR-210-3p affects changes in gene expression, metabolism, apoptosis and …
From protein design to the energy landscape of a cold unfolding protein
Understanding protein folding is crucial for protein sciences. The conformational spaces and
energy landscapes of cold (unfolded) protein states, as well as the associated transitions …
energy landscapes of cold (unfolded) protein states, as well as the associated transitions …
Light from a firefly at temperatures considerably higher and lower than normal
MM Rabha, U Sharma, AG Barua - Scientific Reports, 2021 - nature.com
Bioluminescence emissions from a few species of fireflies have been studied at different
temperatures. Variations in the flash-duration have been observed and interesting …
temperatures. Variations in the flash-duration have been observed and interesting …
NMR as a tool to investigate the processes of mitochondrial and cytosolic iron-sulfur cluster biosynthesis
Iron-sulfur (Fe-S) clusters, the ubiquitous protein cofactors found in all kingdoms of life,
perform a myriad of functions including nitrogen fixation, ribosome assembly, DNA repair …
perform a myriad of functions including nitrogen fixation, ribosome assembly, DNA repair …
Cold denaturation of the HIV-1 protease monomer
HI Rösner, M Caldarini, A Prestel, MA Vanoni… - Biochemistry, 2017 - ACS Publications
The human immunodeficiency virus-1 (HIV-1) protease is a complex protein that in its active
form adopts a homodimer dominated by β-sheet structures. We have discovered a cold …
form adopts a homodimer dominated by β-sheet structures. We have discovered a cold …