Role of microbiota-gut-brain axis in regulating dopaminergic signaling

S Hamamah, A Aghazarian, A Nazaryan, A Hajnal… - Biomedicines, 2022 - mdpi.com
Dopamine is a neurotransmitter that plays a critical role both peripherally and centrally in
vital functions such as cognition, reward, satiety, voluntary motor movements, pleasure, and …

The gut-lung axis in cystic fibrosis

CE Price, GA O'Toole - Journal of bacteriology, 2021 - Am Soc Microbiol
Cystic fibrosis (CF) is a heritable, multiorgan disease that impacts all tissues that normally
express cystic fibrosis transmembrane conductance regulator (CFTR) protein. While the …

Elexacaftor/tezacaftor/ivacaftor and gastrointestinal outcomes in cystic fibrosis: Report of promise-GI

SJ Schwarzenberg, PT Vu, M Skalland… - Journal of Cystic …, 2023 - Elsevier
Background Elexacaftor/tezacaftor/ivacaftor (ETI) improves pulmonary disease in people
with cystic fibrosis (PwCF), but its effect on gastrointestinal symptoms, which also affect …

The use of fecal calprotectin testing in paediatric disorders: a position paper of the European Society for Paediatric Gastroenterology and Nutrition Gastroenterology …

CR Koninckx, E Donat, MA Benninga… - Journal of pediatric …, 2021 - journals.lww.com
Objectives: The aim of the study was to review the evidence regarding the clinical use and
value of fecal calprotectin (FC) measurements in different gastrointestinal disorders in …

The microbiome in cystic fibrosis pulmonary disease

A Françoise, G Héry-Arnaud - Genes, 2020 - mdpi.com
Cystic fibrosis (CF) is a genetic disease with mutational changes leading to profound
dysbiosis, both pulmonary and intestinal, from a very young age. This dysbiosis plays an …

The extrapulmonary effects of cystic fibrosis transmembrane conductance regulator modulators in cystic fibrosis

V Sergeev, FY Chou, GY Lam, CM Hamilton… - Annals of the …, 2020 - atsjournals.org
The effects of cystic fibrosis (CF) transmembrane conductance regulator (CFTR) modulators
on lung function, pulmonary exacerbations, and quality of life have been well documented …

Cystic fibrosis-related gut dysbiosis: a systematic review

LR Caley, H White, MC de Goffau, RA Floto… - Digestive Diseases and …, 2023 - Springer
Abstract Background and Aims Cystic Fibrosis (CF) is associated with gut dysbiosis, local
and systemic inflammation, and impaired immune function. Gut microbiota dysbiosis results …

[HTML][HTML] PROMISE: working with the CF community to understand emerging clinical and research needs for those treated with highly effective CFTR modulator therapy

DP Nichols, SH Donaldson, CA Frederick… - Journal of Cystic …, 2021 - Elsevier
Highly effective CFTR modulator drug therapy is increasingly available to those with cystic
fibrosis. Multiple observational research studies are now being conducted to better …

Cystic fibrosis, CFTR, and colorectal cancer

P Scott, K Anderson, M Singhania… - International journal of …, 2020 - mdpi.com
Cystic fibrosis (CF), caused by biallelic inactivating mutations in the cystic fibrosis
transmembrane conductance regulator (CFTR) gene, has recently been categorized as a …

[HTML][HTML] A restructuring of microbiome niche space is associated with Elexacaftor-Tezacaftor-Ivacaftor therapy in the cystic fibrosis lung

LM Sosinski, KA Neugebauer, LAJ Ghuneim… - Journal of Cystic …, 2022 - Elsevier
Abstract Background Elexacaftor-Tezacaftor-Ivacaftor (ETI) therapy is showing promising
efficacy for treatment of cystic fibrosis (CF) and is becoming more widely available since …