Type I photosensitizers revitalizing photodynamic oncotherapy

D Chen, Q Xu, W Wang, J Shao, W Huang, X Dong - Small, 2021 - Wiley Online Library
Photodynamic therapy (PDT) has shown great potential for tumor treatment with merits of
non‐invasiveness, high selectivity, and minimal side effects. However, conventional type II …

Phototherapeutic anticancer strategies with first-row transition metal complexes: a critical review

L Gourdon, K Cariou, G Gasser - Chemical Society Reviews, 2022 - pubs.rsc.org
Photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) are therapeutic
techniques based on a photosensitizer (PS) and light. These techniques allow the spatial …

The unique features and promises of phthalocyanines as advanced photosensitisers for photodynamic therapy of cancer

PC Lo, MS Rodríguez-Morgade, RK Pandey… - Chemical Society …, 2020 - pubs.rsc.org
Phthalocyanines exhibit superior photoproperties that make them a surely attractive class of
photosensitisers for photodynamic therapy of cancer. Several derivatives are at various …

[HTML][HTML] Photodynamic therapy combined with immunotherapy: Recent advances and future research directions

M Warszyńska, P Repetowski, JM Dąbrowski - Coordination Chemistry …, 2023 - Elsevier
Innovative anticancer therapies based on the activation of the immune system offer promise
in the battle against cancers resistant to traditional treatments. Examples of such therapeutic …

Type I photodynamic therapy by organic–inorganic hybrid materials: From strategies to applications

YY Wang, YC Liu, H Sun, DS Guo - Coordination Chemistry Reviews, 2019 - Elsevier
Photodynamic therapy (PDT) is a promising approach for treatment of cancer and bacterial
infection. Upon excitation by light, photosensitizers (PSs) produce reactive oxygen species …

Recent advances in strategies for overcoming hypoxia in photodynamic therapy of cancer

B Pucelik, A Sułek, A Barzowska, JM Dąbrowski - Cancer Letters, 2020 - Elsevier
The selectivity of photodynamic therapy (PDT) derived from the tailored accumulation of
photosensitizing drug (photosensitizer; PS) in the tumor microenvironment (TME), and from …

Zinc (II) phthalocyanines as photosensitizers for antitumor photodynamic therapy

LP Roguin, N Chiarante, MCG Vior, J Marino - The international journal of …, 2019 - Elsevier
Photodynamic therapy (PDT) is a highly specific and clinically approved method for cancer
treatment in which a nontoxic drug known as photosensitizer (PS) is administered to a …

Reactive oxygen species in photodynamic therapy: mechanisms of their generation and potentiation

JM Dąbrowski - Advances in inorganic chemistry, 2017 - Elsevier
Reactive oxygen species (ROS) play key roles in cell signaling systems and homeostasis,
and they are also fundamental to photodynamic therapy (PDT). PDT efficacy can be affected …

[HTML][HTML] Bacteriochlorins and their metal complexes as NIR-absorbing photosensitizers: Properties, mechanisms, and applications

B Pucelik, A Sułek, JM Dąbrowski - Coordination Chemistry Reviews, 2020 - Elsevier
Bacterichlorins possess a characteristic intense electronic absorption in the near-infrared
part of the electromagnetic radiation (NIR) from 700 nm up to 900 nm, where endogenous …

Bioinorganic antimicrobial strategies in the resistance era

A Regiel-Futyra, JM Dąbrowski, O Mazuryk… - Coordination Chemistry …, 2017 - Elsevier
Abstract The emergence of Multi-Drug-Resistant (MDR) organisms has become a major
worldwide clinical problem. The extensive and routine use of the first-line antibiotics to …