Mechanistic pathogenesis of endothelial dysfunction in diabetic nephropathy and retinopathy

J Yang, Z Liu - Frontiers in endocrinology, 2022 - frontiersin.org
Diabetic nephropathy (DN) and diabetic retinopathy (DR) are microvascular complications of
diabetes. Microvascular endothelial cells are thought to be the major targets of …

Diabetic muscular atrophy: molecular mechanisms and promising therapies

Y Shen, M Li, K Wang, G Qi, H Liu, W Wang… - Frontiers in …, 2022 - frontiersin.org
Diabetes mellitus (DM) is a typical chronic disease that can be divided into 2 types,
dependent on insulin deficiency or insulin resistance. Incidences of diabetic complications …

[HTML][HTML] Insulin resistance

AM Freeman, N Pennings - 2018 - europepmc.org
Objectives: Articulate the acquired and genetic causes of insulin resistance. Explain the
pathophysiology of insulin resistance. Summarize the 3 arms in the management of insulin …

Understanding the role of hyperglycemia and the molecular mechanism associated with diabetic neuropathy and possible therapeutic strategies

M Kaur, S Misra, P Swarnkar, P Patel, BD Kurmi… - Biochemical …, 2023 - Elsevier
Diabetic neuropathy is a neuro-degenerative disorder that encompasses numerous factors
that impact peripheral nerves in the context of diabetes mellitus (DM). Diabetic peripheral …

Polyphenols-rich polyherbal mixture attenuates hepatorenal impairment, dyslipidaemia, oxidative stress and inflammation in alloxan-induced diabetic rats

B Aslam, A Hussain, ZUD Sindhu, S Nigar… - Journal of Applied …, 2023 - Taylor & Francis
Effects of polyherbal mixture on hepatorenal injury and dyslipidaemia in alloxan-induced
diabetic rats were evaluated. Alloxan monohydrate (120 mg/kg, ip) was injected into Wistar …

[HTML][HTML] Association between metformin and vitamin B12 deficiency in patients with type 2 diabetes

E Sayedali, AE Yalin, S Yalin - World journal of diabetes, 2023 - ncbi.nlm.nih.gov
Diabetes mellitus (DM) is still one of the most common diseases worldwide, and its
prevalence is still increasing globally. According to the American and European …

Recent advances in biomolecular patho-mechanistic pathways behind the development and progression of diabetic neuropathy

Y Ratan, A Rajput, A Pareek, A Pareek, R Kaur… - Biomedicines, 2024 - mdpi.com
Diabetic neuropathy (DN) is a neurodegenerative disorder that is primarily characterized by
distal sensory loss, reduced mobility, and foot ulcers that may potentially lead to amputation …

Garden Cress Seed Oil Abrogates Testicular Oxidative Injury and NF-kB-Mediated Inflammation in Diabetic Mice

R Abu-Khudir, GM Badr, HI Abd El-Moaty… - International Journal of …, 2023 - mdpi.com
Diabetes mellitus is a metabolic disorder associated with various complications
encompassing male reproductive dysfunction. The present study aimed to investigate the …

Targeting autophagy with natural products as a potential therapeutic approach for diabetic microangiopathy

F Liu, L Zhao, T Wu, W Yu, J Li, W Wang… - Frontiers in …, 2024 - frontiersin.org
As the quality of life improves, the incidence of diabetes mellitus and its microvascular
complications (DMC) continues to increase, posing a threat to people's health and …

[HTML][HTML] Retinal Microvascular Changes in Association with Endothelial Glycocalyx Damage and Arterial Stiffness in Patients with Diabetes Mellitus Type 2: A Cross …

C Agapitou, TN Sergentanis, J Thymis… - Journal of Personalized …, 2024 - mdpi.com
Purpose: To evaluate the potential association between endothelial glycocalyx damage, as
well as arterial stiffness, and the retinal changes on optical coherence tomography (OCT) …