MicroRNA-21 expression as a prognostic biomarker in oral cancer: systematic review and meta-analysis

M Dioguardi, F Spirito, D Sovereto, M Alovisi… - International journal of …, 2022 - mdpi.com
Oral carcinoma represents one of the main carcinomas of the head and neck region, with a 5-
year survival rate of less than 50%. Smoking and tobacco use are recognized risk factors …

Oral human papillomavirus benign lesions and HPV-related cancer in healthy children: a systematic review

F Di Spirito, G Pantaleo, MP Di Palo, A Amato… - Cancers, 2023 - mdpi.com
Simple Summary The present systematic review aimed to gain deeper insight into the
epidemiology, clinical presentation, and histopathology of HPV-related benign and …

Role of microbiota in viral infections and pathological progression

T Mizutani, A Ishizaka, M Koga, T Tsutsumi… - Viruses, 2022 - mdpi.com
Viral infections are influenced by various microorganisms in the environment surrounding
the target tissue, and the correlation between the type and balance of commensal microbiota …

Nanocarrier-based drug delivery system with dual targeting and NIR/pH response for synergistic treatment of oral squamous cell carcinoma

R Li, C Wan, Y Li, X Jiao, T Liu, Y Gu, R Gao… - Colloids and Surfaces B …, 2024 - Elsevier
Oral squamous cell carcinoma (OSCC) is highly heterogeneous and aggressive, but
therapies based on single-targeted nanoparticles frequently address these tumors as a …

The Potential microRNA Prognostic Signature in HNSCCs: A Systematic Review

M Dioguardi, F Spirito, G Iacovelli, D Sovereto… - Non-coding RNA, 2023 - mdpi.com
Head and neck squamous cell carcinomas (HNSCCs) are often diagnosed at advanced
stages, incurring significant high mortality and morbidity. Several microRNAs (miRs) have …

Tumor-suppressive and immunomodulating activity of miR-30a-3p and miR-30e-3p in HNSCC cells and tumoroids

O Conrad, M Burgy, S Foppolo, A Jehl, A Thiéry… - International Journal of …, 2023 - mdpi.com
Head and neck squamous cell carcinomas (HNSCCs) are heterogeneous tumors, well
known for their frequent relapsing nature. To counter recurrence, biomarkers for early …

Oral bacteriome and oral potentially malignant disorders: A systematic review of the associations

P Pignatelli, MC Curia, G Tenore, D Bondi… - Archives of Oral …, 2024 - Elsevier
INTRODUCTION Periodontal bacteria can infiltrate the epithelium, activate signaling
pathways, induce inflammation, and block natural killer and cytotoxic cells, all of which …

Diagnostic, prognostic, and therapeutic role for angiogenesis markers in head and neck squamous cell carcinoma: a narrative review

L Alessandrini, L Astolfi, A Daloiso, M Sbaraglia… - International Journal of …, 2023 - mdpi.com
Despite refinements to diagnostic and therapeutic approaches over the last two decades,
the outcome of patients with head and neck squamous cell carcinoma (HNSCC) has not …

Oral bacteria, virus and fungi in saliva and tissue samples from adult subjects with Oral squamous cell carcinoma: an umbrella review

F Di Spirito, MP Di Palo, V Folliero, D Cannata… - Cancers, 2023 - mdpi.com
Simple Summary Given the putative or recognized role of oral microorganisms and oral
dysbiosis in oral carcinogenesis and the technological advances in microbial research …

The prognostic role of miR-31 in head and neck squamous cell carcinoma: systematic review and meta-analysis with trial sequential analysis

M Dioguardi, F Spirito, D Sovereto, M Alovisi… - International Journal of …, 2022 - mdpi.com
Background: Head and neck squamous cell carcinoma (HNSCC) is the sixth most common
cancer worldwide with high recurrence, metastasis, and poor treatment outcome. Prognostic …