Biological activity of plant-based carvacrol and thymol and their impact on human health and food quality

NB Rathod, P Kulawik, F Ozogul, JM Regenstein… - Trends in Food Science …, 2021 - Elsevier
Background There is an increased consumer demand for products derived from natural
sources or containing natural compounds used to preserve or improve food quality and/or …

Structural basis of potential inhibitors targeting SARS-CoV-2 main protease

HM Mengist, T Dilnessa, T ** - Frontiers in Chemistry, 2021 - frontiersin.org
The Coronavirus disease-19 (COVID-19) pandemic is still devastating the world causing
significant social, economic, and political chaos. Corresponding to the absence of globally …

COVID-19 and therapy with essential oils having antiviral, anti-inflammatory, and immunomodulatory properties

M Asif, M Saleem, M Saadullah, HS Yaseen… - …, 2020 - Springer
Abstract Coronavirus disease of 2019 (COVID-19) has emerged as a global health threat.
Unfortunately, there are very limited approved drugs available with established efficacy …

Plants metabolites: possibility of natural therapeutics against the COVID-19 pandemic

FR Bhuiyan, S Howlader, T Raihan, M Hasan - Frontiers in medicine, 2020 - frontiersin.org
COVID-19, a disease induced by SARS-CoV-2 (Severe Acute Respiratory Syndrome
Coronavirus-2), has been the cause of a worldwide pandemic. Though extensive research …

An updated and comprehensive review of the antiviral potential of essential oils and their chemical constituents with special focus on their mechanism of action …

AR Wani, K Yadav, A Khursheed, MA Rather - Microbial Pathogenesis, 2021 - Elsevier
Essential oils and their chemical constituents have been reported with well documented
antimicrobial effects against a range of bacterial, fungal and viral pathogens. By definition …

In silico investigation of phytoconstituents from Indian medicinal herb 'Tinospora cordifolia (giloy)' against SARS-CoV-2 (COVID-19) by molecular dynamics approach

P Chowdhury - Journal of Biomolecular Structure and Dynamics, 2021 - Taylor & Francis
The recent appearance of COVID-19 virus has created a global crisis due to unavailability of
any vaccine or drug that can effectively and deterministically work against it. Naturally …

Identification of bioactive molecule from Withania somnifera (Ashwagandha) as SARS-CoV-2 main protease inhibitor

MK Tripathi, P Singh, S Sharma, TP Singh… - Journal of …, 2021 - Taylor & Francis
SARS-CoV-2 is the causative agent of COVID-19 and has been declared as pandemic
disease by World Health Organization. Lack of targeted therapeutics and vaccines for …

Potential bioactive glycosylated flavonoids as SARS-CoV-2 main protease inhibitors: A molecular docking and simulation studies

SA Cherrak, H Merzouk, N Mokhtari-Soulimane - Plos one, 2020 - journals.plos.org
A novel coronavirus responsible of acute respiratory infection closely related to SARS-CoV
has recently emerged. So far there is no consensus for drug treatment to stop the spread of …

Natural products can be used in therapeutic management of COVID-19: Probable mechanistic insights

S Ali, M Alam, F Khatoon, U Fatima, AM Elasbali… - Biomedicine & …, 2022 - Elsevier
The unexpected emergence of the new Coronavirus disease (COVID-19) has affected more
than three hundred million individuals and resulted in more than five million deaths …

In silico Screening of Natural Compounds as Potential Inhibitors of SARS-CoV-2 Main Protease and Spike RBD: Targets for COVID-19

DM Teli, MB Shah, MT Chhabria - Frontiers in molecular biosciences, 2021 - frontiersin.org
Historically, plants have been sought after as bio-factories for the production of diverse
chemical compounds that offer a multitude of possibilities to cure diseases. To combat the …