Messenger RNA (mRNA)‐based therapy has emerged as a powerful, safe, and rapidly
scalable therapeutic approach that involves technologies for both mRNA itself and the …

Altered redox metabolism is one of the hallmarks of tumor cells, which not only contributes to
tumor proliferation, metastasis, and immune evasion, but also has great relevance to …

Blood-brain barrier (BBB) obstructing brain drug delivery severely hampers the therapeutic
efficacy towards glioma. An efficient brain delivery strategy is of paramount importance for …

In addition to inhibiting persistent inflammation, phosphatase and tensin homolog deleted
from chromosome 10 (PTEN) is known as an important therapeutic target for alleviating …

Central nervous system (CNS) diseases, ranging from brain cancers to neurodegenerative
disorders like dementia and acute conditions such as strokes, have been heavily burdening …

In the last decade, messenger ribonucleic acid (mRNA)-based drugs have gained great
interest in both immunotherapy and non-immunogenic applications. This surge in interest …

Glioblastoma multiforme (GBM) is a highly malignant brain tumor with a poor prognosis and
limited treatment options. Drug delivery by stimuli-responsive nanocarriers holds great …

Immunotherapy is regarded as one of the most promising approaches for treating tumors,
with a multitude of immunotherapeutic thoughts currently under consideration for the lethal …

Brain disorders represent a significant challenge in medical science due to the formidable
blood–brain barrier (BBB), which severely limits the penetration of conventional …

mRNA vaccines are leading a medical revolution. mRNA technologies utilize the host's own
cells as bio-factories to produce proteins that serve as antigens. This revolutionary approach …