Chronic kidney disease (CKD) is a public health epidemic that affects millions of people
worldwide. Presence of CKD predisposes individuals to high risks of end-stage renal …

Chronic Kidney Disease–Mineral and Bone Disorder (CKD-MBD) comprises alterations in
calcium, phosphorus, parathyroid hormone (PTH), Vitamin D, and fibroblast growth factor-23 …

Rationale & Objective Bone biopsy remains the gold standard for diagnosing renal
osteodystrophy as comparable noninvasive alternatives have yet to be established. This …

An increased circulating level of fibroblast growth factor 23 (FGF23) is an independent risk
factor for mortality, cardiovascular disease, and progression of chronic kidney disease …

Background Kidney transplantation corrects or improves many complications of chronic
kidney disease, but its impact on disordered mineral metabolism is incompletely understood …

Recent reports of several bone-derived substances, some of which have hormonal
properties, have shed new light on the bone–cardiovascular axis. Deranged concentrations …

Over the past few years there have been considerable advances in our understanding of the
physiological regulation of mineral homeostasis. One of the most important breakthroughs is …

Patients with chronic kidney disease (CKD) are at a high risk for cardiovascular disease
(CVD), and approximately half of all deaths among patients with CKD are a direct result of …

Recent studies of inherited disorders of phosphate metabolism have shed new light on the
understanding of phosphate metabolism. Phosphate has important functions in the body and …

After kidney transplantation, mineral and bone disorders are associated with higher risk of
fractures and consequent morbidity and mortality. Disorders of calcium and phosphorus …