Ancient DNA analysis

L Orlando, R Allaby, P Skoglund… - Nature reviews …, 2021 - nature.com
Although the first ancient DNA molecules were extracted more than three decades ago, the
first ancient nuclear genomes could only be characterized after high-throughput sequencing …

Peopling of the Americas as inferred from ancient genomics

E Willerslev, DJ Meltzer - Nature, 2021 - nature.com
In less than a decade, analyses of ancient genomes have transformed our understanding of
the Indigenous peopling and population history of the Americas. These studies have shown …

The Allen Ancient DNA Resource (AADR) a curated compendium of ancient human genomes

S Mallick, A Micco, M Mah, H Ringbauer, I Lazaridis… - Scientific Data, 2024 - nature.com
More than two hundred papers have reported genome-wide data from ancient humans.
While the raw data for the vast majority are fully publicly available testifying to the …

On the limits of fitting complex models of population history to f-statistics

R Maier, P Flegontov, O Flegontova, U Işıldak… - Elife, 2023 - elifesciences.org
Our understanding of population history in deep time has been assisted by fitting admixture
graphs (AGs) to data: models that specify the ordering of population splits and mixtures …

[HTML][HTML] Initial Upper Palaeolithic humans in Europe had recent Neanderthal ancestry

M Hajdinjak, F Mafessoni, L Skov, B Vernot, A Hübner… - Nature, 2021 - nature.com
Modern humans appeared in Europe by at least 45,000 years ago 1, 2, 3, 4, 5, but the extent
of their interactions with Neanderthals, who disappeared by about 40,000 years ago 6, and …

Dog domestication and the dual dispersal of people and dogs into the Americas

AR Perri, TR Feuerborn, LAF Frantz… - Proceedings of the …, 2021 - National Acad Sciences
Advances in the isolation and sequencing of ancient DNA have begun to reveal the
population histories of both people and dogs. Over the last 10,000 y, the genetic signatures …

The population history of northeastern Siberia since the Pleistocene

M Sikora, VV Pitulko, VC Sousa, ME Allentoft, L Vinner… - Nature, 2019 - nature.com
Northeastern Siberia has been inhabited by humans for more than 40,000 years but its deep
population history remains poorly understood. Here we investigate the late Pleistocene …

Imputation of ancient human genomes

B Sousa da Mota, S Rubinacci, DI Cruz Dávalos… - Nature …, 2023 - nature.com
Due to postmortem DNA degradation and microbial colonization, most ancient genomes
have low depth of coverage, hindering genotype calling. Genotype imputation can improve …

The deep population history of northern East Asia from the Late Pleistocene to the Holocene

X Mao, H Zhang, S Qiao, Y Liu, F Chang, P **e… - Cell, 2021 - cell.com
Summary Northern East Asia was inhabited by modern humans as early as 40 thousand
years ago (ka), as demonstrated by the Tianyuan individual. Using genome-wide data …

Reconstructing the deep population history of Central and South America

C Posth, N Nakatsuka, I Lazaridis, P Skoglund… - Cell, 2018 - cell.com
We report genome-wide ancient DNA from 49 individuals forming four parallel time transects
in Belize, Brazil, the Central Andes, and the Southern Cone, each dating to at least∼ 9,000 …