Metabolomic epidemiology is the high-throughput study of the relationship between
metabolites and health-related traits. This emerging and rapidly growing field has improved …

As researchers are increasingly able to collect data on a large scale from multiple clinical
and omics modalities, multi-omics integration is becoming a critical component of …

The application of large-scale metabolomic profiling provides new opportunities for realizing
the potential of omics-based precision medicine for asthma. By leveraging data from over …

Background The metabolomic signatures of short-and long-term exposure to PM 2.5 have
been reported and linked to inflammation and oxidative stress. However, little is known …

Background Young children with rhinovirus (RV) infection—particularly bronchiolitis—are at
high risk for develo** childhood asthma. Emerging evidence suggests clinical …

Asthma is a complex respiratory disease considered as the most common chronic condition
in children. A large genetic contribution to asthma susceptibility is predicted by the clustering …

Rationale: A link among sphingolipids, 17q21 genetic variants, and childhood asthma has
been suggested, but the underlying mechanisms and characteristics of such an asthma …

Previous studies have explored the relationships of air pollution and metabolic profiles with
lung function. However, the metabolites linking air pollution and lung function and the …

Current management of severe asthma relying either on guidelines (bulk approach) or on
disease phenotypes (stratified approach) did not improve the burden of the disease. Several …

Approaches to the identification of metabolites have progressed from early biochemical
pathway evaluation to modern high-dimensional metabolomics, a powerful tool to identify …