The majority of cancer patients receive radiotherapy during the course of treatment,
delivered with curative intent for local tumor control or as part of a multimodality regimen …

Radiotherapy (RT) is an effective treatment option for cancer patients, which induces the
production of reactive oxygen species (ROS) and causes oxidative stress (OS), leading to …

Five-year survival for human papilloma virus-unrelated head and neck squamous cell
carcinomas remain below 50%. We assessed the safety of administering combination …

Purpose: Patients with resected, local–regionally advanced, head and neck squamous cell
carcinoma (HNSCC) have a one-year disease-free survival (DFS) rate of 65%–69% despite …

Treatment options for patients with hepatocellular carcinoma are rapidly changing based on
positive results from phase 3 trials of targeted and immune-based therapies. More agents …

Purpose: Radiotherapy (RT) can transform the immune landscape and render poorly
immunogenic tumors sensitive to PD-L1 inhibition. Here, we established that the response to …

Solid cancers comprise a large number of new cases and deaths from cancer each year
globally. There are a number of strategies for addressing tumors raised from solid organs …

Purpose: ATR inhibitors (ATRi) are in early phase clinical trials and have been shown to
sensitize to chemotherapy and radiotherapy preclinically. Limited data have been published …

Radiotherapy is one of the most common modalities for the treatment of cancer. One of the
most promising effects of radiotherapy is immunologic cell death and the release of danger …

Radiotherapy is a common modality for more than half of cancer patients. Classically,
radiation is known as a strategy to kill cancer cells via direct interaction with DNA or …