Nanotechnology: a promising approach for delivery of neuroprotective drugs

S Naqvi, A Panghal, SJS Flora - Frontiers in Neuroscience, 2020 - frontiersin.org
Central nervous system (CNS) disorders especially neurodegenerative disorders are the
major challenge for public health and demand the great attention of researchers to protect …

The use of TPGS in drug delivery systems to overcome biological barriers

MT Luiz, LD Di Filippo, RC Alves, VHS Araújo… - European Polymer …, 2021 - Elsevier
Nanotechnology has been applied in the medicine field to improve the treatment of a wide
range of diseases. However, to reach the nanomedicines delivery to desirable target tissue …

Nanotechnology for the diagnosis and treatment of Alzheimer's disease: A bibliometric analysis

L Li, R He, H Yan, Z Leng, S Zhu, Z Gu - Nano Today, 2022 - Elsevier
As a progressive, irreversible neurodegenerative disease, Alzheimer's disease (AD)
continues to be a serious public health problem worldwide. Currently, the most available …

Lipid-based nanoformulations in the treatment of neurological disorders

FH Pottoo, S Sharma, MN Javed, MA Barkat… - Drug Metabolism …, 2020 - Taylor & Francis
The neurological disorders affect millions of people worldwide, and are bracketed as the
foremost basis of disability-adjusted life years (DALYs). The treatment options are …

Lipid-based nanocarriers via nose-to-brain pathway for central nervous system disorders

TT Nguyen, TTD Nguyen, NMA Tran, G Van Vo - Neurochemical research, 2022 - Springer
Neurodegenerative disorders are distinguished by the gradual deterioration of the nervous
system's structure and function due to oxidative stress, mitochondrial dysfunction, protein …

[HTML][HTML] Intranasal administration of edaravone nanoparticles improves its stability and brain bioavailability

Y Lu, JTW Wang, N Li, X Zhu, Y Li, S Bansal… - Journal of Controlled …, 2023 - Elsevier
The clinical application of EDV, a potent antioxidant drug approved for amyotrophic lateral
sclerosis (ALS), is limited by its short biological half-life and poor water solubility …

Two decades-long journey from riluzole to edaravone: revisiting the clinical pharmacokinetics of the only two amyotrophic lateral sclerosis therapeutics

RP Dash, RJ Babu, NR Srinivas - Clinical pharmacokinetics, 2018 - Springer
The recent approval of edaravone has provided an intravenous option to treat amyotrophic
lateral sclerosis (ALS) in addition to the existing oral agent, riluzole. The present work was …

Oral delivery of lycopene-loaded microemulsion for brain-targeting: preparation, characterization, pharmacokinetic evaluation and tissue distribution

Y Guo, X Mao, J Zhang, P Sun, H Wang, Y Zhang… - Drug …, 2019 - Taylor & Francis
Lycopene is considered as a promising neuroprotector with multiple bioactivities, while its
therapeutic use in neurological disorders is restricted due to low solubility, instability and …

Anti-GPC3 antibody-modified sorafenib-loaded nanoparticles significantly inhibited HepG2 hepatocellular carcinoma

X Tang, L Chen, A Li, S Cai, Y Zhang, X Liu, Z Jiang… - Drug …, 2018 - Taylor & Francis
Sorafenib (SFB) has improved the treatment of hepatocellular carcinoma (HCC) and has
fewer severe side effects than other agents used for that purpose. However, due to a lack of …

Development of Abraham model correlations for describing solute transfer into transcutol based on molar solubility ratios for pharmaceutical and other organic …

A Varadharajan, S Sinha, A Xu, A Daniel, K Kim… - Journal of Solution …, 2023 - Springer
Mole fraction solubilities have been measured for anthracene, benzoic acid, benzoin, 4-tert-
butylbenzoic acid, 1-chloroanthraquinone, 3-chlorobenzoic acid, 4-chlorobenzoic acid, 4 …