Nanotechnology: a promising approach for delivery of neuroprotective drugs
Central nervous system (CNS) disorders especially neurodegenerative disorders are the
major challenge for public health and demand the great attention of researchers to protect …
major challenge for public health and demand the great attention of researchers to protect …
The use of TPGS in drug delivery systems to overcome biological barriers
Nanotechnology has been applied in the medicine field to improve the treatment of a wide
range of diseases. However, to reach the nanomedicines delivery to desirable target tissue …
range of diseases. However, to reach the nanomedicines delivery to desirable target tissue …
Nanotechnology for the diagnosis and treatment of Alzheimer's disease: A bibliometric analysis
As a progressive, irreversible neurodegenerative disease, Alzheimer's disease (AD)
continues to be a serious public health problem worldwide. Currently, the most available …
continues to be a serious public health problem worldwide. Currently, the most available …
Lipid-based nanoformulations in the treatment of neurological disorders
The neurological disorders affect millions of people worldwide, and are bracketed as the
foremost basis of disability-adjusted life years (DALYs). The treatment options are …
foremost basis of disability-adjusted life years (DALYs). The treatment options are …
Lipid-based nanocarriers via nose-to-brain pathway for central nervous system disorders
Neurodegenerative disorders are distinguished by the gradual deterioration of the nervous
system's structure and function due to oxidative stress, mitochondrial dysfunction, protein …
system's structure and function due to oxidative stress, mitochondrial dysfunction, protein …
[HTML][HTML] Intranasal administration of edaravone nanoparticles improves its stability and brain bioavailability
Y Lu, JTW Wang, N Li, X Zhu, Y Li, S Bansal… - Journal of Controlled …, 2023 - Elsevier
The clinical application of EDV, a potent antioxidant drug approved for amyotrophic lateral
sclerosis (ALS), is limited by its short biological half-life and poor water solubility …
sclerosis (ALS), is limited by its short biological half-life and poor water solubility …
Two decades-long journey from riluzole to edaravone: revisiting the clinical pharmacokinetics of the only two amyotrophic lateral sclerosis therapeutics
The recent approval of edaravone has provided an intravenous option to treat amyotrophic
lateral sclerosis (ALS) in addition to the existing oral agent, riluzole. The present work was …
lateral sclerosis (ALS) in addition to the existing oral agent, riluzole. The present work was …
Oral delivery of lycopene-loaded microemulsion for brain-targeting: preparation, characterization, pharmacokinetic evaluation and tissue distribution
Y Guo, X Mao, J Zhang, P Sun, H Wang, Y Zhang… - Drug …, 2019 - Taylor & Francis
Lycopene is considered as a promising neuroprotector with multiple bioactivities, while its
therapeutic use in neurological disorders is restricted due to low solubility, instability and …
therapeutic use in neurological disorders is restricted due to low solubility, instability and …
Anti-GPC3 antibody-modified sorafenib-loaded nanoparticles significantly inhibited HepG2 hepatocellular carcinoma
X Tang, L Chen, A Li, S Cai, Y Zhang, X Liu, Z Jiang… - Drug …, 2018 - Taylor & Francis
Sorafenib (SFB) has improved the treatment of hepatocellular carcinoma (HCC) and has
fewer severe side effects than other agents used for that purpose. However, due to a lack of …
fewer severe side effects than other agents used for that purpose. However, due to a lack of …
Development of Abraham model correlations for describing solute transfer into transcutol based on molar solubility ratios for pharmaceutical and other organic …
A Varadharajan, S Sinha, A Xu, A Daniel, K Kim… - Journal of Solution …, 2023 - Springer
Mole fraction solubilities have been measured for anthracene, benzoic acid, benzoin, 4-tert-
butylbenzoic acid, 1-chloroanthraquinone, 3-chlorobenzoic acid, 4-chlorobenzoic acid, 4 …
butylbenzoic acid, 1-chloroanthraquinone, 3-chlorobenzoic acid, 4-chlorobenzoic acid, 4 …