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[PDF][PDF] Animal cell cycles and their control
CELL CYCLE CONTROL IN ANIMALS 443 established in many cases. Nonetheless, the
phosphorylation of nuclear lamins to promote nuclear disassembly (25, 31, 38-40), and the …
phosphorylation of nuclear lamins to promote nuclear disassembly (25, 31, 38-40), and the …
MAP Kinase Pathways in the YeastSaccharomyces cerevisiae
SUMMARY A cascade of three protein kinases known as a mitogen-activated protein kinase
(MAPK) cascade is commonly found as part of the signaling pathways in eukaryotic cells …
(MAPK) cascade is commonly found as part of the signaling pathways in eukaryotic cells …
Cyclin D1 is a nuclear protein required for cell cycle progression in G1.
A cascade of events is triggered upon the addition of growth factor to quiescent mammalian
cells, which ultimately restarts proliferation by inducing the transition from G0/G1 to S-phase …
cells, which ultimately restarts proliferation by inducing the transition from G0/G1 to S-phase …
p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest.
Cell-cell contact and TGF-beta can arrest the cell cycle in G1. Mv1Lu mink epithelial cells
arrested by either mechanism are incapable of assembling active complexes containing the …
arrested by either mechanism are incapable of assembling active complexes containing the …
Cyclin A is required at two points in the human cell cycle.
Cyclins play a fundamental role in regulating cell cycle events in all eukaryotic cells. The
human cyclin A gene was identified as the site of integration of hepatitis B virus in a …
human cyclin A gene was identified as the site of integration of hepatitis B virus in a …
A genome-wide transcriptional analysis of the mitotic cell cycle
Progression through the eukaryotic cell cycle is known to be both regulated and
accompanied by periodic fluctuation in the expression levels of numerous genes. We report …
accompanied by periodic fluctuation in the expression levels of numerous genes. We report …
Effects of aneuploidy on cellular physiology and cell division in haploid yeast
Aneuploidy is a condition frequently found in tumor cells, but its effect on cellular physiology
is not known. We have characterized one aspect of aneuploidy: the gain of extra …
is not known. We have characterized one aspect of aneuploidy: the gain of extra …
Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression
The yeast TOR2 gene encodes an essential 282 kd phosphatidylinositol (PI) 3-kinase
homolog. TOR2 is related to the catalytic subunit of bovine PI 3-kinase and to yeast VPS34 …
homolog. TOR2 is related to the catalytic subunit of bovine PI 3-kinase and to yeast VPS34 …
Molecular themes in oncogenesis
JM Bishop - Cell, 1991 - Elsevier
No inkling has been found of what happens in a cell when it becomes neoplastic, and how
this state of affairs is passed on when it multiplies. A favorite explanation has been that …
this state of affairs is passed on when it multiplies. A favorite explanation has been that …
TOR controls translation initiation and early G1 progression in yeast.
Saccharomyces cerevisiae cells treated with the immunosuppressant rapamycin or depleted
for the targets of rapamycin TOR1 and TOR2 arrest growth in the early G1 phase of the cell …
for the targets of rapamycin TOR1 and TOR2 arrest growth in the early G1 phase of the cell …