Polymeric nanoparticles for drug delivery

MA Beach, U Nayanathara, Y Gao, C Zhang… - Chemical …, 2024 - ACS Publications
The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …

A global review on short peptides: frontiers and perspectives

V Apostolopoulos, J Bojarska, TT Chai, S Elnagdy… - Molecules, 2021 - mdpi.com
Peptides are fragments of proteins that carry out biological functions. They act as signaling
entities via all domains of life and interfere with protein-protein interactions, which are …

Developments in vaccine adjuvants

FZ Firdaus, M Skwarczynski, I Toth - Vaccine Design: Methods and …, 2022 - Springer
Vaccines, including subunit, recombinant, and conjugate vaccines, require the use of an
immunostimulator/adjuvant for maximum efficacy. Adjuvants not only enhance the strength …

Polymeric microneedles for controlled transdermal drug delivery

P Singh, A Carrier, Y Chen, S Lin, J Wang, S Cui… - Journal of controlled …, 2019 - Elsevier
Polymeric microneedle (MN) systems are interesting transdermal drug delivery systems
because of their controlled drug delivery, tunable properties, and ease of patient self …

Cyclic dipeptides: The biological and structural landscape with special focus on the anti-cancer proline-based scaffold

J Bojarska, A Mieczkowski, ZM Ziora, M Skwarczynski… - Biomolecules, 2021 - mdpi.com
Cyclic dipeptides, also know as diketopiperazines (DKP), the simplest cyclic forms of
peptides widespread in nature, are unsurpassed in their structural and bio-functional …

[HTML][HTML] Chemical conjugation strategies for the development of protein-based subunit nanovaccines

L Lu, VT Duong, AO Shalash, M Skwarczynski, I Toth - Vaccines, 2021 - mdpi.com
The production of subunit nanovaccines relies heavily on the development of a vaccine
delivery system that is safe and efficient at delivering antigens to the target site …

Cancer vaccines: adjuvant potency, importance of age, lifestyle, and treatments

S Cuzzubbo, S Mangsbo, D Nagarajan… - Frontiers in …, 2021 - frontiersin.org
Although the discovery and characterization of multiple tumor antigens have sparked the
development of many antigen/derived cancer vaccines, many are poorly immunogenic and …

Long-acting vaccine delivery systems

P Walvekar, P Kumar, YE Choonara - Advanced Drug Delivery Reviews, 2023 - Elsevier
Bolus vaccines are often administered multiple times due to rapid clearance and reduced
transportation to draining lymph nodes resulting in inadequate activation of T and B …

Hydrogel-based microneedles of chitosan derivatives for drug delivery

H Wei, S Liu, Z Tong, T Chen, M Yang, Y Guo… - Reactive and Functional …, 2022 - Elsevier
Hydrogel-based microneedles have been developed to enhance the effectiveness of
transdermal drug delivery in various applications due to its ability to penetrate skin's stratum …

Biosafety materials: an emerging new research direction of materials science from the COVID-19 outbreak

Y Yu, F Bu, H Zhou, Y Wang, J Cui, X Wang… - Materials Chemistry …, 2020 - pubs.rsc.org
The coronavirus disease 2019 (COVID-19) pandemic is a serious biosafety event that is
causing a severe impact on the global society and economy. Thus, the importance of …