Abstract mRNA-based drugs have tremendous potential as clinical treatments, however, a
major challenge in realizing this drug class will promise to develop methods for safely …

Zika virus (ZIKV), an emerging arthropod-borne flavivirus, was first isolated in Uganda in
1947 from monkeys and first detected in humans in Nigeria in 1952; it has been associated …

The Zika pandemic sparked intense interest in whether immune interactions among dengue
virus serotypes 1 to 4 (DENV1 to-4) extend to the closely related Zika virus (ZIKV). We …

Dengue is the most common viral infection spread by mosquitoes, prevalent in tropical
countries. The acute dengue virus (DENV) infection is a benign and primarily febrile illness …

The recently emerged Zika virus (ZIKV) spread to the Americas, causing a spectrum of
congenital diseases including microcephaly in newborn and Guillain-Barré syndrome (GBS) …

An effective HIV-1 vaccine must elicit broadly neutralizing antibodies (bnAbs) against highly
diverse Envelope glycoproteins (Env). Since Env with the longest hypervariable (HV) loops …

As exemplified by the ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) pandemic, there is a strong demand for rapid high-throughput isolation pipelines to …

The repeat emergence of SARS-CoV-2 variants of concern (VoC) with decreased
susceptibility to vaccine-elicited antibodies highlights the need to develop next-generation …

Prevention of viral escape and increased coverage against severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) variants of concern require therapeutic monoclonal …

Dengue viruses 1-4 (DENV 1-4) and Zika virus (ZIKV) are closely related flaviviruses
transmitted by Aedes mosquitoes that co-circulate in Asia, the Americas, Africa, and …