An extensive literature on childhood adversity and neurodevelopment has emerged over the
past decade. We evaluate two conceptual models of adversity and neurodevelopment—the …

Upon increasing levels of threat, animals activate qualitatively different defensive modes,
including freezing and active fight-or-flight reactions. Whereas freezing is a form of …

The brain is constituted of multiple networks of functionally correlated brain areas, out of
which the default-mode network (DMN) is the largest. Most existing research into the DMN …

Depression is associated with social risk factors, social impairments and poor social
functioning. This paper gives an overview of these social aspects using the NIMH Research …

Over the past three decades, insights into the role of the cerebellum in emotional processing
have substantially increased. Indeed, methodological refinements in cerebellar lesion …

Given the importance of emotion regulation as a transdiagnostic factor in the development of
psychopathology, a myriad of neuroimaging studies has investigated its neural …

Resting state functional connectivity reveals intrinsic, spontaneous networks that elucidate
the functional architecture of the human brain. However, valid statistical analysis used to …

Aggression and violence represent a significant public health concern and a clinical
challenge for the mental healthcare provider. A great deal has been revealed regarding the …

The cerebral cortex communicates with the cerebellum via polysynaptic circuits. Separate
regions of the cerebellum are connected to distinct cerebral areas, forming a complex …

Recent human imaging and animal studies highlight the importance of frontoamygdala
circuitry in the regulation of emotional behavior and its disruption in anxiety-related …