Anxiety is experienced in response to threats that are distal or uncertain, involving changes
in one's subjective state, autonomic responses, and behavior. Defensive and physiologic …

Highlights•Populations of the amygdala complex drive positive and negative
valence.•Valence coding can be defined by neural responses to positive and negative …

Co** with threatening situations requires both identifying stimuli that predict danger and
selecting adaptive behavioural responses to survive. The dorsomedial prefrontal cortex …

Numerous animal studies have demonstrated that fear acquisition and expression rely on
the coordinated activity of medial prefrontal cortex (mPFC) and amygdala and that theta …

Traumatic events result in vivid and enduring fear memories. Suppressing the retrieval of
these memories is central to behavioral therapies for pathological fear. The medial prefrontal …

Basolateral amygdala (BLA) projects widely across the macaque frontal cortex, and
amygdalo-frontal projections are critical for appropriate emotional responding and decision …

Memory for aversive events is central to survival but can become maladaptive in psychiatric
disorders. Memory enhancement for emotional events is thought to depend on amygdala …

Social behaviors recruit multiple cognitive operations that require interactions between
cortical and subcortical brain regions. Interareal synchrony may facilitate such interactions …

Animals learn to fear conditioned sound stimuli (CSs) that accompany aversive
unconditioned stimuli (USs). Auditory cortex (ACx) circuits reorganize to support auditory …

Learned fear and safety are associated with distinct oscillatory states in the basolateral
amygdala (BLA) and medial prefrontal cortex (mPFC). To determine if and how these …