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MicroRNAs in extracellular vesicles: Sorting mechanisms, diagnostic value, isolation, and detection technology
D Xu, K Di, B Fan, J Wu, X Gu, Y Sun… - … in bioengineering and …, 2022 - frontiersin.org
MicroRNAs (miRNAs) are a class of short, single-stranded, noncoding RNAs, with a length
of about 18–22 nucleotides. Extracellular vesicles (EVs) are derived from cells and play a …
of about 18–22 nucleotides. Extracellular vesicles (EVs) are derived from cells and play a …
The miR-200 family of microRNAs: fine tuners of epithelial-mesenchymal transition and circulating cancer biomarkers
Simple Summary MicroRNAs (miRNAs) are small RNA molecules that regulate gene
expression by blocking translation or inducing degradation of specific gene transcripts. The …
expression by blocking translation or inducing degradation of specific gene transcripts. The …
Triple-negative breast cancer: current treatment strategies and factors of negative prognosis
A Baranova, M Krasnoselskyi… - Journal of medicine …, 2022 - pmc.ncbi.nlm.nih.gov
Breast cancer is the most common cancer in women and the most common cause of death
in working-age women. According to the results of immunohistochemical studies, 10–20% of …
in working-age women. According to the results of immunohistochemical studies, 10–20% of …
[HTML][HTML] Genetic heterogeneity, tumor microenvironment and immunotherapy in triple-negative breast cancer
E Kudelova, M Smolar, V Holubekova… - International Journal of …, 2022 - mdpi.com
Heterogeneity of triple-negative breast cancer is well known at clinical, histopathological,
and molecular levels. Genomic instability and greater mutation rates, which may result in the …
and molecular levels. Genomic instability and greater mutation rates, which may result in the …
Non-coding RNAs as liquid biopsy biomarkers in cancer
Although non-coding RNAs have long been considered as non-functional “junk” RNAs,
accumulating evidence in the past decade indicates that they play a critical role in …
accumulating evidence in the past decade indicates that they play a critical role in …
A review of multi-omics data integration through deep learning approaches for disease diagnosis, prognosis, and treatment
Accurate diagnosis is the key to providing prompt and explicit treatment and disease
management. The recognized biological method for the molecular diagnosis of infectious …
management. The recognized biological method for the molecular diagnosis of infectious …
Notch signaling in acute inflammation and sepsis
N Gallenstein, L Tichy, MA Weigand… - International Journal of …, 2023 - mdpi.com
Notch signaling, a highly conserved pathway in mammals, is crucial for differentiation and
homeostasis of immune cells. Besides, this pathway is also directly involved in the …
homeostasis of immune cells. Besides, this pathway is also directly involved in the …
[HTML][HTML] based screen-printed electrode to detect miRNA-652 associated to triple-negative breast cancer
Triple-negative breast cancer (TNBC) is one of the most aggressive and lethal types of BC,
affecting mostly young women and its diagnosis is difficult and requires invasive methods …
affecting mostly young women and its diagnosis is difficult and requires invasive methods …
lncRNA-microRNA axis in cancer drug resistance: particular focus on signaling pathways
Cancer drug resistance remains a formidable challenge in modern oncology, necessitating
innovative therapeutic strategies. The convergence of intricate regulatory networks involving …
innovative therapeutic strategies. The convergence of intricate regulatory networks involving …
[HTML][HTML] New molecular mechanisms and clinical impact of circRNAs in human cancer
G Fontemaggi, C Turco, G Esposito, S Di Agostino - Cancers, 2021 - mdpi.com
Simple Summary Circular RNAs (circRNAs) belong to a new class of non-coding RNAs
implicated in cellular physiological functions but also in the evolution of various human …
implicated in cellular physiological functions but also in the evolution of various human …