MicroRNAs in extracellular vesicles: Sorting mechanisms, diagnostic value, isolation, and detection technology

D Xu, K Di, B Fan, J Wu, X Gu, Y Sun… - … in bioengineering and …, 2022 - frontiersin.org
MicroRNAs (miRNAs) are a class of short, single-stranded, noncoding RNAs, with a length
of about 18–22 nucleotides. Extracellular vesicles (EVs) are derived from cells and play a …

The miR-200 family of microRNAs: fine tuners of epithelial-mesenchymal transition and circulating cancer biomarkers

I Cavallari, F Ciccarese, E Sharova, L Urso… - Cancers, 2021 - mdpi.com
Simple Summary MicroRNAs (miRNAs) are small RNA molecules that regulate gene
expression by blocking translation or inducing degradation of specific gene transcripts. The …

Triple-negative breast cancer: current treatment strategies and factors of negative prognosis

A Baranova, M Krasnoselskyi… - Journal of medicine …, 2022 - pmc.ncbi.nlm.nih.gov
Breast cancer is the most common cancer in women and the most common cause of death
in working-age women. According to the results of immunohistochemical studies, 10–20% of …

[HTML][HTML] Genetic heterogeneity, tumor microenvironment and immunotherapy in triple-negative breast cancer

E Kudelova, M Smolar, V Holubekova… - International Journal of …, 2022 - mdpi.com
Heterogeneity of triple-negative breast cancer is well known at clinical, histopathological,
and molecular levels. Genomic instability and greater mutation rates, which may result in the …

Non-coding RNAs as liquid biopsy biomarkers in cancer

S Toden, A Goel - British journal of cancer, 2022 - nature.com
Although non-coding RNAs have long been considered as non-functional “junk” RNAs,
accumulating evidence in the past decade indicates that they play a critical role in …

A review of multi-omics data integration through deep learning approaches for disease diagnosis, prognosis, and treatment

JS Wekesa, M Kimwele - Frontiers in genetics, 2023 - frontiersin.org
Accurate diagnosis is the key to providing prompt and explicit treatment and disease
management. The recognized biological method for the molecular diagnosis of infectious …

Notch signaling in acute inflammation and sepsis

N Gallenstein, L Tichy, MA Weigand… - International Journal of …, 2023 - mdpi.com
Notch signaling, a highly conserved pathway in mammals, is crucial for differentiation and
homeostasis of immune cells. Besides, this pathway is also directly involved in the …

[HTML][HTML] based screen-printed electrode to detect miRNA-652 associated to triple-negative breast cancer

A Raucci, W Cimmino, SP Grosso, N Normanno… - Electrochimica …, 2024 - Elsevier
Triple-negative breast cancer (TNBC) is one of the most aggressive and lethal types of BC,
affecting mostly young women and its diagnosis is difficult and requires invasive methods …

lncRNA-microRNA axis in cancer drug resistance: particular focus on signaling pathways

RO Saleh, MTS Al-Ouqaili, E Ali, S Alhajlah… - Medical Oncology, 2024 - Springer
Cancer drug resistance remains a formidable challenge in modern oncology, necessitating
innovative therapeutic strategies. The convergence of intricate regulatory networks involving …

[HTML][HTML] New molecular mechanisms and clinical impact of circRNAs in human cancer

G Fontemaggi, C Turco, G Esposito, S Di Agostino - Cancers, 2021 - mdpi.com
Simple Summary Circular RNAs (circRNAs) belong to a new class of non-coding RNAs
implicated in cellular physiological functions but also in the evolution of various human …